ASD

GO:0008593 regulation of Notch signaling pathway (20)

GeneInput weightStandardRank
FBXW7--198
MEG3--238
ASCL1--413
DLL3--1847
BMP7--1137
HEY1--1280
JAG1--11704
HEY2--3174
GATA2--13291
WNT1--4383
FGF10--14532
DTX1--5290
NFKBIA--5569
OVOL2--10428
POSTN--10779
MESP1--13805
NRARP--14597
NOD2--121514
TP63--122528
C12orf52--24985

Network

GO:0008593

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
DLL3delta-like 3 (Drosophila) Entrez:10683  Ensembl: ENSG00000090932  HGNC: 2909  HPRD: 04140 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
MEG3maternally expressed 3 (non-protein coding)
ASCL1achaete-scute complex homolog 1 (Drosophila)
DLL3delta-like 3 (Drosophila)
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
MEG3MEG3maternally expressed 3 (non-protein coding)
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
DLL3DLL3delta-like 3 (Drosophila)
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University