ASD

GO:0043525 positive regulation of neuron apoptosis (33)

GeneInput weightStandardRank
SRPK2--171
NF10.251372
UBE2M--381
ASCL1--413
NR3C1--496
JUN--511
CDK5R1--586
TGFB2--834
EPHA7--837
HRK--1660
CDK50.2513194
BCL2L11--3469
ATM--13622
MUSK--4006
PTPRF--5040
FASLG--15523
MAP2K7--5837
AGRN0.2516010
PMAIP1--7385
CASP2--9480
BAX--9833
PCSK9--10760
RHOC--11655
MAP3K11--12938
TNF0.25115243
ITGA1--15500
TP530.25118277
RAPSN--20521
NCF2--122977
CASP6--23087
IL18--24018
CASP7--25028
NQO1--25542

Network

GO:0043525

Network
Enrichment
NameDescriptionExternal IDs
SRPK2SRSF protein kinase 2 Entrez:6733  HPRD: 04280  Ensembl: ENSG00000135250  HGNC: 11306 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
UBE2Mubiquitin-conjugating enzyme E2M Entrez:9040  HPRD: 04414  HGNC: 12491  Ensembl: ENSG00000130725 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SRPK2SRSF protein kinase 2
NF1neurofibromin 1
UBE2Mubiquitin-conjugating enzyme E2M
ASCL1achaete-scute complex homolog 1 (Drosophila)
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Query geneGeneGene descriptionEdge score
SRPK2SRPK2SRSF protein kinase 2
NF1NF1neurofibromin 1
UBE2MUBE2Mubiquitin-conjugating enzyme E2M
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Troyanskaya Laboratory - Princeton University