ASD

GO:0048635 negative regulation of muscle organ development (14)

GeneInput weightStandardRank
LEF1--1499
USP2--3856
GSK3A--4141
MSTN--4329
FGF3--4687
NGFR0.2516212
BMP4--16499
SOX15--6674
TWIST1--16980
FGF8--18543
IL6--112695
LUC7L--13845
SIRT2--22147
YBX3--23237

Network

GO:0048635

Network
Enrichment
NameDescriptionExternal IDs
LEF1lymphoid enhancer-binding factor 1 Entrez:51176  HGNC: 6551  Ensembl: ENSG00000138795  HPRD: 01075 
USP2ubiquitin specific peptidase 2 Entrez:9099  Ensembl: ENSG00000036672  HGNC: 12618  HPRD: 05287 
GSK3Aglycogen synthase kinase 3 alpha Entrez:2931  HGNC: 4616  HPRD: 06002  Ensembl: ENSG00000105723 
MSTNmyostatin Entrez:2660  HPRD: 03474  Ensembl: ENSG00000138379  HGNC: 4223 
FGF3fibroblast growth factor 3 Entrez:2248  HGNC: 3681  HPRD: 01289 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LEF1lymphoid enhancer-binding factor 1
USP2ubiquitin specific peptidase 2
GSK3Aglycogen synthase kinase 3 alpha
MSTNmyostatin
FGF3fibroblast growth factor 3
Query geneGeneGene descriptionEdge score
LEF1LEF1lymphoid enhancer-binding factor 1
USP2USP2ubiquitin specific peptidase 2
GSK3AGSK3Aglycogen synthase kinase 3 alpha
MSTNMSTNmyostatin
FGF3FGF3fibroblast growth factor 3

Troyanskaya Laboratory - Princeton University