ASD

GO:0070997 neuron death (20)

GeneInput weightStandardRank
SIAH1--223
GRIK20.51232
PARK20.251952
BAG5--1229
ERBB3--1350
APP--1515
PPARGC1A--1909
BCL20.2512485
GAPDH--2661
MAX--3376
TNFRSF21--3997
BNIP3--6953
LIG4--17187
POU4F3--17242
LRRK2--18802
PIGT--19097
ZNF746--20237
NLRP1--20532
BID--22640
AIFM1--25591

Network

GO:0070997

Network
Enrichment
NameDescriptionExternal IDs
SIAH1siah E3 ubiquitin protein ligase 1 Entrez:6477  Ensembl: ENSG00000196470  HGNC: 10857  HPRD: 03736 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
BAG5BCL2-associated athanogene 5 Entrez:9529  HGNC: 941  HPRD: 04862  Ensembl: ENSG00000166170 
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 Entrez:2065  HGNC: 3431  Ensembl: ENSG00000065361  HPRD: 01820 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SIAH1siah E3 ubiquitin protein ligase 1
GRIK2glutamate receptor, ionotropic, kainate 2
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
BAG5BCL2-associated athanogene 5
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Query geneGeneGene descriptionEdge score
SIAH1SIAH1siah E3 ubiquitin protein ligase 1
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
BAG5BAG5BCL2-associated athanogene 5
ERBB3ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Troyanskaya Laboratory - Princeton University