ASD

GO:0045665 negative regulation of neuron differentiation (49)

GeneInput weightStandardRank
TTC3--68
SOX2--1200
ASCL1--413
PAX60.251544
OLIG2--619
FOXG1--661
CNTN2--674
ZNF536--839
SOX9--1970
NR2E10.251977
ID4--1009
NKX2-2--1120
BMP7--1137
MIB10.2511153
ZHX2--1216
APP--1515
PHOX2B--1917
ISL1--1974
DLL1--2053
ID2--2154
SOX3--2303
CNTN41.012492
SOX21--2559
FOXA2--2645
RTN4--2735
NOTCH1--12865
DIXDC1--3734
ITGB1--3903
GDF11--4104
SLC6A40.2514137
LMX1A--4236
HOXA2--4273
SOX8--4609
HES5--4919
DTX1--5290
HES10.2515912
GLI3--16261
TLX3--6462
IRX3--7476
LBX1--9134
REST--9779
RHOC--11655
NBN--116066
TP73--18810
CTDSP1--21639
NOTCH3--22114
CALR--22152
PRPF19--22991
ASPM--124942

Network

GO:0045665

Network
Enrichment
NameDescriptionExternal IDs
TTC3tetratricopeptide repeat domain 3 Entrez:7267  HPRD: 03773  HGNC: 12393  Ensembl: ENSG00000182670 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
OLIG2oligodendrocyte lineage transcription factor 2 Entrez:10215  HPRD: 07334  Ensembl: ENSG00000205927  HGNC: 9398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TTC3tetratricopeptide repeat domain 3
SOX2SRY (sex determining region Y)-box 2
ASCL1achaete-scute complex homolog 1 (Drosophila)
PAX6paired box 6
OLIG2oligodendrocyte lineage transcription factor 2
Query geneGeneGene descriptionEdge score
TTC3TTC3tetratricopeptide repeat domain 3
SOX2SOX2SRY (sex determining region Y)-box 2
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
PAX6PAX6paired box 6
OLIG2OLIG2oligodendrocyte lineage transcription factor 2

Troyanskaya Laboratory - Princeton University