Gene | Input weight | Standard | Rank | |
PPP2CA | - | - | 20 | |
CAMK2B | 0.25 | 1 | 55 | |
KALRN | - | - | 56 | |
YWHAB | 0.25 | 1 | 107 | |
TRIO | 0.5 | 1 | 111 | |
NELL1 | - | - | 132 | |
ABR | - | - | 160 | |
PRKCE | - | - | 204 | |
ARHGEF7 | - | - | 215 | |
GRIK2 | 0.5 | 1 | 232 | |
ARHGEF4 | - | - | 265 | |
EP300 | - | -1 | 318 | |
PPP3R1 | - | - | 321 | |
TIAM1 | - | - | 325 | |
RASGRF1 | - | - | 335 | |
ARHGEF12 | - | -1 | 393 | |
CUL1 | - | - | 478 | |
ACVR1B | - | - | 510 | |
BCLAF1 | - | - | 549 | |
PPP2R5C | - | - | 555 | |
CRH | - | - | 563 | |
USP7 | - | - | 573 | |
ARHGEF11 | - | - | 705 | |
SOS1 | - | -1 | 810 | |
SMAD3 | - | - | 823 | |
LYST | - | -1 | 831 | |
ARHGEF9 | - | -1 | 875 | |
MCF2 | - | - | 892 | |
TOPORS | - | -1 | 894 | |
RYR2 | - | -1 | 959 | |
ADORA1 | - | - | 960 | |
YWHAE | - | - | 995 | |
AKT1 | 0.25 | 1 | 1020 | |
PRKCA | - | - | 1027 | |
HIPK2 | - | - | 1051 | |
FOXO3 | - | - | 1056 | |
MCF2L | - | - | 1059 | |
TUBB4B | - | - | 1087 | |
CUL3 | 1.0 | 1 | 1093 | |
MAPK1 | - | - | 1128 | |
SST | - | - | 1139 | |
CDKN1B | - | - | 1162 | |
PPP2R1A | - | - | 1163 | |
SOS2 | - | - | 1181 | |
FGD1 | - | -1 | 1182 | |
DYNLL1 | - | - | 1191 | |
DYRK2 | - | - | 1203 | |
MAPK8 | - | - | 1214 | |
MAP3K5 | - | - | 1220 | |
DLC1 | - | - | 1282 | |
BAD | - | - | 1290 | |
BAG6 | - | - | 1305 | |
COL4A3 | - | -1 | 1327 | |
DPF1 | - | - | 1368 | |
PTEN | 1.0 | 1 | 1389 | |
LEF1 | - | - | 1499 | |
APP | - | - | 1515 | |
RNF41 | - | - | 1596 | |
RAC1 | - | - | 1617 | |
HRK | - | - | 1660 | |
AKAP13 | - | - | 1679 | |
DCC | - | - | 1687 | |
ITSN1 | - | - | 1789 | |
HIP1 | - | - | 1797 | |
ARHGEF2 | - | - | 1819 | |
DAPK1 | - | - | 1848 | |
SPECC1L | - | - | 1912 | |
CUL2 | - | - | 2097 | |
TP53INP1 | - | - | 2121 | |
NDUFA13 | - | -1 | 2204 | |
MAPK9 | - | - | 2237 | |
CUL5 | - | - | 2323 | |
ABL1 | - | - | 2404 | |
RASGRF2 | - | - | 2414 | |
TP53BP2 | - | - | 2477 | |
BCL2 | 0.25 | 1 | 2485 | |
PRUNE2 | - | - | 2565 | |
TIA1 | - | - | 2578 | |
PLAGL2 | - | - | 2692 | |
PREX1 | - | - | 2760 | |
TUBB | - | - | 2800 | |
TBX5 | - | - | 2836 | |
VAV2 | - | - | 2850 | |
VAV3 | - | - | 2908 | |
MAP3K10 | - | - | 2968 | |
FNIP2 | - | - | 3028 | |
TIAM2 | - | - | 3070 | |
ARHGEF17 | - | - | 3189 | |
LALBA | - | - | 3200 | |
MSH6 | - | -1 | 3445 | |
KLF10 | - | - | 3457 | |
BCL2L11 | - | - | 3469 | |
DEDD | - | - | 3535 | |
CEBPB | - | - | 3598 | |
ATM | - | -1 | 3622 | |
TNFRSF25 | - | - | 3659 | |
TIAL1 | - | - | 4048 | |
MAGED1 | - | - | 4068 | |
ITM2C | - | - | 4102 | |
ARHGEF3 | - | - | 4159 | |
ARHGEF18 | - | - | 4257 | |
MAL | - | - | 4319 | |
SERINC3 | - | - | 4428 | |
WT1 | - | -1 | 4514 | |
CEBPG | - | - | 4660 | |
SENP1 | - | - | 4701 | |
INHA | - | - | 4765 | |
TERF1 | - | - | 4825 | |
DAPK3 | - | - | 4958 | |
NLRP3 | 0.25 | 1 | 4959 | |
HRAS | 0.25 | 1 | 5086 | |
APAF1 | 0.25 | 1 | 5149 | |
FEM1B | - | - | 5206 | |
IFNB1 | - | - | 5250 | |
XPA | - | -1 | 5296 | |
TNFRSF19 | - | - | 5520 | |
FASLG | - | -1 | 5523 | |
JMY | - | - | 5725 | |
WWOX | - | -1 | 5791 | |
TFPT | - | - | 5796 | |
ETS1 | - | - | 5943 | |
SIVA1 | - | - | 5973 | |
STK11 | - | -1 | 6000 | |
CIDEA | - | - | 6211 | |
NGFR | 0.25 | 1 | 6212 | |
NGF | 0.25 | 1 | 6229 | |
MSH2 | - | -1 | 6311 | |
RUNX3 | - | - | 6322 | |
BMF | - | - | 6376 | |
BCL2L1 | - | - | 6563 | |
CASP8AP2 | - | - | 6582 | |
CIDEC | - | - | 6596 | |
PCBP4 | - | - | 6634 | |
NOTCH2 | - | -1 | 6664 | |
CASP3 | 0.25 | 1 | 6694 | |
UBC | - | - | 6756 | |
PHLDA1 | - | - | 6783 | |
PTH | - | - | 6947 | |
BNIP3 | - | - | 6953 | |
ERCC3 | - | -1 | 7110 | |
WNT7B | - | - | 7113 | |
TGFBR1 | - | -1 | 7268 | |
XIAP | - | - | 7332 | |
PMAIP1 | - | - | 7385 | |
FGD4 | - | -1 | 7457 | |
NET1 | - | - | 7500 | |
FOXL2 | - | -1 | 7521 | |
PPP1R13B | - | - | 7576 | |
CDIP1 | - | - | 7580 | |
IFNA2 | - | - | 7694 | |
CDKN1A | - | - | 7714 | |
BCL3 | - | - | 7998 | |
NOX5 | - | - | 8007 | |
CD24 | - | -1 | 8102 | |
NMT1 | - | - | 8219 | |
DAP3 | - | - | 8246 | |
IL19 | - | - | 8257 | |
ADORA2A | 0.25 | 1 | 8408 | |
DAXX | - | - | 8508 | |
C6 | - | - | 8602 | |
C9 | - | - | 8637 | |
FGD3 | - | - | 8790 | |
DAP | - | - | 8832 | |
AIFM3 | - | - | 8980 | |
NGFRAP1 | - | - | 9211 | |
CYCS | - | - | 9251 | |
NGEF | - | - | 9344 | |
CASP2 | - | - | 9480 | |
BOK | - | - | 9611 | |
CD3E | - | - | 9680 | |
PRKRA | - | - | 9728 | |
BAX | - | - | 9833 | |
ERN1 | - | - | 9939 | |
BNIP3L | - | - | 10405 | |
PLEKHG2 | - | - | 10476 | |
PLEKHG5 | - | - | 10686 | |
MBD4 | 0.25 | 1 | 10712 | |
PCSK9 | - | - | 10760 | |
NDUFS3 | - | -1 | 10928 | |
TRAF3 | - | - | 11036 | |
TRAF6 | - | - | 11055 | |
CASP14 | - | - | 11126 | |
CD5 | - | - | 11220 | |
TNFSF8 | - | - | 11375 | |
GPX1 | 0.25 | 1 | 11644 | |
GSDMA | - | - | 11652 | |
PDCD7 | - | - | 11756 | |
GCH1 | 0.25 | 1 | 11867 | |
SPN | - | - | 12057 | |
DEDD2 | - | - | 12101 | |
ZNF443 | - | - | 12108 | |
PDCD6 | - | - | 12294 | |
NR4A1 | - | - | 12498 | |
SH3GLB1 | - | - | 12690 | |
SH3RF1 | - | - | 12767 | |
UACA | - | - | 12955 | |
TRIM35 | - | - | 12958 | |
TGFB3 | - | -1 | 13097 | |
TNFRSF9 | - | - | 13284 | |
AGT | - | -1 | 13305 | |
UNC13B | - | - | 13412 | |
APH1A | 0.5 | 1 | 13440 | |
PAWR | - | - | 13478 | |
TNFRSF10B | - | - | 13570 | |
PRKRAP1 | - | - | 13599 | |
PRMT2 | - | - | 13677 | |
PLAGL1 | - | - | 13916 | |
DPF2 | - | - | 13968 | |
STK17B | - | - | 14417 | |
SORT1 | - | - | 14441 | |
PRODH | 0.25 | 1 | 14818 | |
USP28 | - | - | 15068 | |
TNF | 0.25 | 1 | 15243 | |
SAP30BP | - | - | 15351 | |
SIK1 | - | - | 15416 | |
ZMAT3 | - | - | 16037 | |
SMNDC1 | - | - | 16907 | |
PPP3CC | - | - | 16922 | |
INHBA | - | - | 16974 | |
RRM2B | - | - | 17077 | |
KLRF2 | - | - | 17790 | |
LTA | - | - | 18082 | |
TP53 | 0.25 | 1 | 18277 | |
SSTR3 | - | - | 18309 | |
PSEN1 | - | - | 18523 | |
TP73 | - | - | 18810 | |
BNIPL | - | - | 19199 | |
ARHGEF6 | - | - | 19241 | |
TLR2 | - | -1 | 19246 | |
LGALS12 | - | - | 19322 | |
CFLAR | - | - | 19385 | |
UBB | - | - | 19448 | |
IKBIP | - | - | 19859 | |
SLAMF7 | - | - | 19864 | |
CLEC2A | - | - | 19949 | |
FGD2 | - | - | 20103 | |
TGFB1 | 0.25 | 1 | 20135 | |
CD2 | - | - | 20392 | |
NLRP1 | - | - | 20532 | |
BBC3 | - | - | 20534 | |
STK17A | - | - | 20564 | |
PSENEN | - | -1 | 20566 | |
CDKN2A | - | -1 | 20587 | |
OBSCN | - | - | 20605 | |
NACC1 | - | - | 20662 | |
FASTK | 0.25 | 1 | 20797 | |
BIK | - | - | 20799 | |
DAPK2 | - | - | 20808 | |
GZMB | - | - | 20809 | |
SART1 | - | - | 20962 | |
TNFSF12 | - | - | 20965 | |
NCSTN | - | -1 | 20988 | |
CASP9 | 0.25 | 1 | 21044 | |
DYNLL2 | - | - | 21102 | |
NME3 | - | - | 21148 | |
UNC13D | - | -1 | 21158 | |
PDCD5 | - | - | 21187 | |
ARHGEF16 | - | - | 21200 | |
BAK1 | - | - | 21229 | |
CD70 | - | - | 21289 | |
ARHGAP4 | - | - | 21362 | |
CD38 | 0.25 | 1 | 21442 | |
EAF2 | - | - | 21685 | |
ERN2 | - | - | 21707 | |
TNFRSF10A | - | - | 21740 | |
ERCC2 | - | -1 | 21804 | |
VDR | - | - | 21837 | |
TICAM1 | - | - | 21880 | |
DFFB | - | - | 21977 | |
C5 | - | -1 | 22004 | |
AEN | - | - | 22019 | |
RIPK3 | - | - | 22030 | |
PYCARD | - | - | 22145 | |
BTK | - | -1 | 22251 | |
TNFSF14 | - | - | 22260 | |
BCL10 | - | -1 | 22368 | |
TPD52L1 | - | - | 22519 | |
TP63 | - | -1 | 22528 | |
NAIF1 | - | - | 22588 | |
BID | - | - | 22640 | |
EIF5A | - | - | 22674 | |
RIPK1 | - | - | 22681 | |
PPARG | - | -1 | 22729 | |
CD27 | - | - | 22836 | |
TNFRSF1A | - | - | 22842 | |
MUL1 | - | - | 22953 | |
SHISA5 | - | - | 23072 | |
CASP6 | - | - | 23087 | |
PSEN2 | - | - | 23095 | |
TGM2 | - | - | 23204 | |
NUDT2 | - | - | 23229 | |
AATF | - | - | 23243 | |
FADD | - | - | 23261 | |
NOD1 | - | - | 23388 | |
DIABLO | - | - | 23456 | |
APOE | 0.25 | 1 | 23516 | |
IKBKG | - | -1 | 23539 | |
DRAM2 | - | - | 23559 | |
SQSTM1 | - | -1 | 23584 | |
TP53I3 | - | - | 23611 | |
TRAF2 | - | - | 23686 | |
IFI27 | - | - | 23825 | |
UTP11L | - | - | 23835 | |
VAV1 | - | - | 23876 | |
CASP10 | - | -1 | 23880 | |
HMOX1 | - | - | 23938 | |
RNF7 | - | - | 23982 | |
CDKN2C | - | - | 24062 | |
CIDEB | - | - | 24163 | |
CUL4A | - | - | 24230 | |
RAB27A | - | - | 24284 | |
EI24 | - | - | 24294 | |
BCL2L13 | - | - | 24304 | |
SMPD2 | - | - | 24309 | |
AIFM2 | - | - | 24314 | |
IFI16 | - | - | 24354 | |
ITGB3BP | - | - | 24372 | |
RPS27A | - | - | 24381 | |
UBA52 | - | - | 24384 | |
APH1B | - | - | 24417 | |
THBS1 | - | - | 24444 | |
MX1 | - | - | 24496 | |
BRCA1 | - | -1 | 24573 | |
CASP8 | - | -1 | 24587 | |
ALOX15B | - | - | 24590 | |
IKBKE | - | - | 24643 | |
FAS | - | -1 | 24697 | |
BNIP1 | - | - | 24721 | |
LCK | - | - | 24753 | |
ECT2 | - | - | 24758 | |
CHEK2 | - | -1 | 24807 | |
HTRA2 | - | -1 | 24821 | |
PHLDA3 | - | - | 24856 | |
CRADD | - | - | 24961 | |
CASP4 | - | - | 24966 | |
CASP7 | - | - | 25028 | |
TRAIP | - | - | 25146 | |
RPS27L | - | - | 25183 | |
TNFSF10 | - | - | 25200 | |
TRADD | - | - | 25265 | |
PML | - | - | 25277 | |
SFN | - | - | 25459 | |
MLH1 | - | -1 | 25513 | |
DFFA | - | - | 25546 | |
RPS3 | - | - | 25585 | |
AIFM1 | - | - | 25591 | |
HTATIP2 | - | - | 25647 | |
NUPR1 | - | - | 25669 | |
RPS3A | - | - | 25775 | |
TM2D1 | - | - | 25807 |
GO:0012502
Name | Description | External IDs |
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | Entrez:5515  HGNC: 9299  HPRD: 08912  |
CAMK2B | calcium/calmodulin-dependent protein kinase II beta | Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127  |
KALRN | kalirin, RhoGEF kinase | Entrez:8997  HPRD: 06859  HGNC: 4814  Ensembl: ENSG00000160145  |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184  |
TRIO | trio Rho guanine nucleotide exchange factor | Entrez:7204  Ensembl: ENSG00000038382  HPRD: 03537  HGNC: 12303  |
Geneset | Type | Freq. (Network vs Genome) | P-Value (FDR Corrected) | Genes |
Gene | Description | Avg. edge score to query | Rank | In geneset | In query |
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | ||||
CAMK2B | calcium/calmodulin-dependent protein kinase II beta | ||||
KALRN | kalirin, RhoGEF kinase | ||||
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | ||||
TRIO | trio Rho guanine nucleotide exchange factor |
Query gene | Gene | Gene description | Edge score |
PPP2CA | PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | |
CAMK2B | CAMK2B | calcium/calmodulin-dependent protein kinase II beta | |
KALRN | KALRN | kalirin, RhoGEF kinase | |
YWHAB | YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | |
TRIO | TRIO | trio Rho guanine nucleotide exchange factor |