ASD

GO:0030262 apoptotic nuclear change (31)

GeneInput weightStandardRank
KPNB1--338
SFRP1--387
NDUFA13--12204
HMGB10.2512379
SOD1--12702
MSX1--13127
HMGB2--3362
MOAP1--4508
ACIN1--5134
FOXQ1--5820
KPNA1--6146
CIDEA--6211
H1F0--6290
CASP30.2516694
BNIP3--6953
FOXL2--17521
CECR2--8318
CYCS--9251
BAX--9833
DEDD2--12101
PPT1--113834
BIRC7--19826
CDKN2A--120587
DNASE1L3--21285
DFFB--21977
TPD52L1--22519
SHARPIN--22710
ENDOG--24105
TOP2A--24765
DFFA--25546
AIFM1--25591

Network

GO:0030262

Network
Enrichment
NameDescriptionExternal IDs
KPNB1karyopherin (importin) beta 1 Entrez:3837  HPRD: 04114  HGNC: 6400 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
NDUFA13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 Entrez:51079  HGNC: 17194  HPRD: 09452 
HMGB1high mobility group box 1 Entrez:3146  HGNC: 4983  HPRD: 01228  Ensembl: ENSG00000189403 
SOD1superoxide dismutase 1, soluble Entrez:6647  HGNC: 11179  Ensembl: ENSG00000142168  HPRD: 00937 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KPNB1karyopherin (importin) beta 1
SFRP1secreted frizzled-related protein 1
NDUFA13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
HMGB1high mobility group box 1
SOD1superoxide dismutase 1, soluble
Query geneGeneGene descriptionEdge score
KPNB1KPNB1karyopherin (importin) beta 1
SFRP1SFRP1secreted frizzled-related protein 1
NDUFA13NDUFA13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
HMGB1HMGB1high mobility group box 1
SOD1SOD1superoxide dismutase 1, soluble

Troyanskaya Laboratory - Princeton University