ASD

GO:0030111 regulation of Wnt receptor signaling pathway (141)

GeneInput weightStandardRank
PPP2CA--20
UBR5--193
SOX2--1200
USP34--231
FGFR2--1237
SOX4--250
FGF9--262
APC0.251266
LRP6--279
SFRP1--387
SALL1--506
CDK140.251536
CSNK1D--699
NLK--712
MACF1--715
CSNK1E0.251752
HMGXB4--781
SMAD3--823
EDA--1925
SOX9--1970
APC2--1115
PPP2R1A--1163
AES--1230
DISC10.511238
TNKS--1414
HDAC2--1440
CXXC4--1490
CHD81.011493
LEF1--1499
LRP4--1500
WNT10B--1517
TLE1--1605
WNT2B--1673
GRB10--1910
MED120.2512052
PPM1A--2070
MCC--2167
STK4--2276
WNT20.2512299
DKK2--2331
SIX3--12494
FGFR3--12640
DLX5--2706
LATS1--2781
SKI--2904
CTNND1--2948
EGR1--3062
CITED1--3064
WNT5A--3319
ZRANB1--3481
DAB2IP--3482
TCF7L20.513548
SIAH2--3729
DIXDC1--3734
SOX17--4024
LECT2--4161
AXIN2--14260
CAPRIN2--4284
TNKS2--4385
AXIN1--14419
MBD2--4518
FGF10--14532
CYLD--14624
RSPO2--4631
DRAXIN--4717
WNT3A--4747
ZNF703--5031
SFRP2--5252
DKK3--5413
PRICKLE1--15552
CTNNBIP1--5675
WWOX--15791
STK11--16000
SOX7--6117
GLI1--6241
GLI3--16261
FOXL1--6313
ZEB2--6361
TLE2--6532
BARX1--6608
SOST--6885
SCYL2--7130
RSPO1--7229
ILK--7305
SFRP4--7310
WNT7A--7312
WNT8A--7814
WNT11--7820
RNF146--7910
FRZB--8105
GPC3--18430
NKX2-50.2518486
BAMBI--8550
TBX18--8991
TSC20.2519351
LRP5--19420
GSC--9702
LATS2--9736
HNF1B--19881
DKK4--10367
APCDD1--10507
PPAP2B--10628
CCNY--10662
KREMEN1--10806
SFRP5--11273
DKK1--11567
TCF7L1--12273
NPHP3--113474
MDFI--13519
MESP1--13805
NRARP--14597
INVS--114708
DDIT3--14883
WNT5B--15534
TAX1BP3--15553
WLS--15707
SHH--118571
DVL1--18924
TLR2--119246
HHEX--19523
POU5F1--19704
FZD6--19921
EMD--120034
NFKB1--20281
JUP--120291
FZD1--20775
TRPM4--20948
STK3--21167
MDFIC--21692
SENP2--21704
WNT4--21809
LRP1--22276
YAP1--22469
PFDN5--23272
GNB2L1--23282
CBY1--23816
SNAI2--123962
COL1A1--124140
WWTR1--24317
DAB2--25338
CAV1--125381

Network

GO:0030111

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
USP34ubiquitin specific peptidase 34 Entrez:9736  HGNC: 20066  HPRD: 11665  Ensembl: ENSG00000115464 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX2SRY (sex determining region Y)-box 2
USP34ubiquitin specific peptidase 34
FGFR2fibroblast growth factor receptor 2
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX2SOX2SRY (sex determining region Y)-box 2
USP34USP34ubiquitin specific peptidase 34
FGFR2FGFR2fibroblast growth factor receptor 2

Troyanskaya Laboratory - Princeton University