ASD

GO:0048634 regulation of muscle organ development (70)

GeneInput weightStandardRank
PLCB1--148
PIK3R10.251150
FGFR2--1237
MEG3--238
FGF9--262
LRP6--279
HDAC4--696
SMAD3--823
NRG10.251936
SOX9--1970
BTG1--1000
ADRB1--1057
LEF1--1499
WNT10B--1517
RPS6KB1--1521
HDAC5--1950
FGFR1--2262
WNT20.2512299
MTPN--2402
HMGCR--2526
SHOX2--2767
TBX5--2836
NOTCH1--12865
CXADR--2887
TBX3--2958
RBM24--3115
HEY2--3174
ZFHX3--13201
HDAC9--3228
RBP4--3448
CDON--3487
USP2--3856
MUSK--4006
GSK3A--4141
MSTN--4329
SOX8--4609
FGF3--4687
BMP10--5102
MKL20.2515140
NOG--15439
MYOCD--5907
AGRN0.2516010
ACVR1--16054
NGFR0.2516212
BMP4--16499
SOX15--6674
BOC--6901
TWIST1--16980
ILK--7305
NEU2--8135
NKX2-50.2518486
FGF8--18543
MBNL3--10070
RBM38--11401
GATA4--112466
IL6--112695
FGF2--13150
LUC7L--13845
GJA10.25113867
NMRK2--14041
SHH--118571
TGFB10.25120135
SIRT2--22147
IGFBP3--22342
YBX3--23237
ADRB20.25123251
FBXO22--23669
CDK1--25053
CCNB1--25174
CENPF--25495

Network

GO:0048634

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
FGFR2fibroblast growth factor receptor 2
MEG3maternally expressed 3 (non-protein coding)
FGF9fibroblast growth factor 9
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
FGFR2FGFR2fibroblast growth factor receptor 2
MEG3MEG3maternally expressed 3 (non-protein coding)
FGF9FGF9fibroblast growth factor 9

Troyanskaya Laboratory - Princeton University