ASD

GO:0010962 regulation of glucan biosynthetic process (21)

GeneInput weightStandardRank
PPP1CA--216
AKT10.2511020
DYRK2--1203
IRS2--11300
IRS1--11374
GRB10--1910
GCK--12660
PPP1CB--2693
IGF10.2512793
AKT2--13912
INSR--15872
ENPP1--16091
SORBS1--6411
PTH--6947
PPP1R3D--7282
C1QTNF2--10034
PPP1R3E--12100
PPP1R3C--12887
MTOR--21095
INS--122047
IGF20.25122401

Network

GO:0010962

Network
Enrichment
NameDescriptionExternal IDs
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme Entrez:5499  Ensembl: ENSG00000172531  HPRD: 15942  HGNC: 9281 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 Entrez:8445  HGNC: 3093  HPRD: 04606 
IRS2insulin receptor substrate 2 Entrez:8660  HPRD: 02878  HGNC: 6126  Ensembl: ENSG00000185950 
IRS1insulin receptor substrate 1 Entrez:3667  HPRD: 00943  HGNC: 6125 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
AKT1v-akt murine thymoma viral oncogene homolog 1
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
IRS2insulin receptor substrate 2
IRS1insulin receptor substrate 1
Query geneGeneGene descriptionEdge score
PPP1CAPPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
DYRK2DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
IRS2IRS2insulin receptor substrate 2
IRS1IRS1insulin receptor substrate 1

Troyanskaya Laboratory - Princeton University