ASD

GO:0022029 telencephalon cell migration (33)

GeneInput weightStandardRank
SLIT1--61
PAFAH1B10.25174
LRP6--279
CDK5R1--586
RELN1.01626
SLIT2--659
CNTN2--674
POU3F2--750
DRD10.251899
NR2E10.251977
NDEL10.2511074
RAC1--1617
ROBO1--2182
FGFR1--2262
EGFR--12546
LRP8--2732
RTN4--2735
CDK50.2513194
LHX6--3241
OGDH--3680
DIXDC1--3734
DRD20.2513749
TNR--3868
NKX2-1--4142
FOXB1--5360
GLI3--16261
CX3CR1--7136
PEX5--17148
CXCL12--7802
LRRK2--18802
PSEN1--18523
ARX0.25121856
PEX13--124461

Network

GO:0022029

Network
Enrichment
NameDescriptionExternal IDs
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35) Entrez:8851  Ensembl: ENSG00000176749  HGNC: 1775  HPRD: 04586 
RELNreelin Entrez:5649  HGNC: 9957  Ensembl: ENSG00000189056  HPRD: 02742 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT1slit homolog 1 (Drosophila)
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
LRP6low density lipoprotein receptor-related protein 6
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
RELNreelin
Query geneGeneGene descriptionEdge score
SLIT1SLIT1slit homolog 1 (Drosophila)
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
LRP6LRP6low density lipoprotein receptor-related protein 6
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
RELNRELNreelin

Troyanskaya Laboratory - Princeton University