ASD

GO:0048010 vascular endothelial growth factor receptor signaling pathway (21)

GeneInput weightStandardRank
BMPR2--1281
PDGFRA--1320
PRKD1--909
PRKD2--2228
NRP20.2512603
NRP1--2807
MAPKAPK2--3870
FLT10.2513953
MAPK14--3975
FLT3--14055
VEGFA0.2514087
KDR0.2514854
PGF--6172
PDGFC--6530
FIGF--6702
FOXC2--10175
FLT4--111028
VEGFB--11980
VEGFC--12850
FOXC1--113793
FOXS1--20143

Network

GO:0048010

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
PRKD1protein kinase D1 Entrez:5587  Ensembl: ENSG00000184304  HPRD: 05668  HGNC: 9407 
PRKD2protein kinase D2 Entrez:25865  Ensembl: ENSG00000105287  HGNC: 17293  HPRD: 09523 
NRP2neuropilin 2 Entrez:8828  HGNC: 8005  Ensembl: ENSG00000118257  HPRD: 03643 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
PRKD1protein kinase D1
PRKD2protein kinase D2
NRP2neuropilin 2
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
PRKD1PRKD1protein kinase D1
PRKD2PRKD2protein kinase D2
NRP2NRP2neuropilin 2

Troyanskaya Laboratory - Princeton University