ASD

GO:0045814 negative regulation of gene expression, epigenetic (27)

GeneInput weightStandardRank
SMARCA4--801
HAT1--1208
SIRT1--1233
BAZ2A--1312
HDAC2--1440
HDAC5--1950
EPC1--2533
SIRT3--2700
DNMT3A--4002
UBR2--4054
UBE2B--4057
CREBZF--4129
UBTF--4174
SIRT4--4652
TNP1--6604
KMT2D--6700
SIRT5--13673
TRIM27--14656
DNMT3B--14663
MBD30.25115779
HILS1--16105
SIRT7--20593
SIRT6--21428
SIRT2--22147
RRP8--22607
HELLS--22974
SUV39H1--24290

Network

GO:0045814

Network
Enrichment
NameDescriptionExternal IDs
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Entrez:6597  HPRD: 04459  HGNC: 11100  Ensembl: ENSG00000127616 
HAT1histone acetyltransferase 1 Entrez:8520  HGNC: 4821  Ensembl: ENSG00000128708  HPRD: 04339 
SIRT1sirtuin 1 Entrez:23411  Ensembl: ENSG00000096717  HPRD: 08381  HGNC: 14929 
BAZ2Abromodomain adjacent to zinc finger domain, 2A Entrez:11176  HGNC: 962  Ensembl: ENSG00000076108  HPRD: 10417 
HDAC2histone deacetylase 2 Entrez:3066  Ensembl: ENSG00000196591  HGNC: 4853  HPRD: 05521 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
HAT1histone acetyltransferase 1
SIRT1sirtuin 1
BAZ2Abromodomain adjacent to zinc finger domain, 2A
HDAC2histone deacetylase 2
Query geneGeneGene descriptionEdge score
SMARCA4SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
HAT1HAT1histone acetyltransferase 1
SIRT1SIRT1sirtuin 1
BAZ2ABAZ2Abromodomain adjacent to zinc finger domain, 2A
HDAC2HDAC2histone deacetylase 2

Troyanskaya Laboratory - Princeton University