ASD

GO:0021872 forebrain generation of neurons (27)

GeneInput weightStandardRank
GNAQ--189
FGFR2--1237
LRP6--279
ASCL1--413
PAX60.251544
NR2E10.251977
BCL11B--1125
LEF1--1499
FGFR1--2262
DLX20.2512357
DLX10.2512400
ATP7A--12483
LHX6--3241
WNT8B--3407
NUMBL--3618
OGDH--3680
LHX8--3904
LHX5--3998
NKX2-1--4142
AXIN1--14419
WNT3A--4747
OTP--5490
GLI3--16261
UQCRQ--6404
NUMB--7848
ATG7--23978
ASPM--124942

Network

GO:0021872

Network
Enrichment
NameDescriptionExternal IDs
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAQguanine nucleotide binding protein (G protein), q polypeptide
FGFR2fibroblast growth factor receptor 2
LRP6low density lipoprotein receptor-related protein 6
ASCL1achaete-scute complex homolog 1 (Drosophila)
PAX6paired box 6
Query geneGeneGene descriptionEdge score
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
FGFR2FGFR2fibroblast growth factor receptor 2
LRP6LRP6low density lipoprotein receptor-related protein 6
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
PAX6PAX6paired box 6

Troyanskaya Laboratory - Princeton University