ASD

GO:0090073 positive regulation of protein homodimerization activity (5)

GeneInput weightStandardRank
MEF2C0.251428
MEF2A--2837
CRBN--4203
TRAF4--4556
TIRAP--20658

Network

GO:0090073

Network
Enrichment
NameDescriptionExternal IDs
MEF2Cmyocyte enhancer factor 2C Entrez:4208  HGNC: 6996  Ensembl: ENSG00000081189  HPRD: 02809 
MEF2Amyocyte enhancer factor 2A Entrez:4205  Ensembl: ENSG00000068305  HGNC: 6993  HPRD: 02807 
CRBNcereblon Entrez:51185  HGNC: 30185  Ensembl: ENSG00000113851  HPRD: 16750 
TRAF4TNF receptor-associated factor 4 Entrez:9618  HPRD: 03915  HGNC: 12034  Ensembl: ENSG00000076604 
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein Entrez:114609  Ensembl: ENSG00000150455  HGNC: 17192 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MEF2Cmyocyte enhancer factor 2C
MEF2Amyocyte enhancer factor 2A
CRBNcereblon
TRAF4TNF receptor-associated factor 4
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein
Query geneGeneGene descriptionEdge score
MEF2CMEF2Cmyocyte enhancer factor 2C
MEF2AMEF2Amyocyte enhancer factor 2A
CRBNCRBNcereblon
TRAF4TRAF4TNF receptor-associated factor 4
TIRAPTIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein

Troyanskaya Laboratory - Princeton University