ASD

GO:0016571 histone methylation (49)

GeneInput weightStandardRank
KMT2A1.0116
SUV420H11.01173
SETD20.251672
PRMT8--817
SATB1--828
WHSC1L1--11055
SUZ12--1188
KMT2E0.511234
EED--1566
KDM6A--1766
KMT2C1.012003
PAXIP1--2915
EHMT2--3182
SETD1B--3231
CTCFL--3489
PRDM5--3909
PRMT1--4008
CARM1--4755
WDR82--4909
MEN1--14917
KMT2D--6700
PRDM9--6886
EHMT10.517204
BAGE3--7700
CXXC1--7956
DOT1L--7980
BAGE4--7982
BAGE5--8527
RBBP5--9373
SMYD2--9412
SETD3--13578
PRMT2--13677
NSD10.25114116
SETD8--14849
SETD7--18622
SUV420H2--19960
SUV39H2--20238
ASH2L--22257
WDR92--22279
SMYD3--22549
EZH2--22623
SETDB20.25122691
PRMT7--22847
DPY30--23146
PRMT6--24226
SUV39H1--24290
WDR5--24720
COPRS--24936
PRMT5--25692

Network

GO:0016571

Network
Enrichment
NameDescriptionExternal IDs
KMT2Alysine (K)-specific methyltransferase 2A Entrez:4297  Ensembl: ENSG00000118058  HGNC: 7132  HPRD: 01162 
SUV420H1suppressor of variegation 4-20 homolog 1 (Drosophila) Entrez:51111  HGNC: 24283  Ensembl: ENSG00000110066  HPRD: 11616 
SETD2SET domain containing 2 Entrez:29072  HGNC: 18420  Ensembl: ENSG00000181555  HPRD: 11043 
PRMT8protein arginine methyltransferase 8 Entrez:56341  HGNC: 5188  Ensembl: ENSG00000111218  HPRD: 11029 
SATB1SATB homeobox 1 Entrez:6304  HPRD: 03647  HGNC: 10541  Ensembl: ENSG00000182568 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KMT2Alysine (K)-specific methyltransferase 2A
SUV420H1suppressor of variegation 4-20 homolog 1 (Drosophila)
SETD2SET domain containing 2
PRMT8protein arginine methyltransferase 8
SATB1SATB homeobox 1
Query geneGeneGene descriptionEdge score
KMT2AKMT2Alysine (K)-specific methyltransferase 2A
SUV420H1SUV420H1suppressor of variegation 4-20 homolog 1 (Drosophila)
SETD2SETD2SET domain containing 2
PRMT8PRMT8protein arginine methyltransferase 8
SATB1SATB1SATB homeobox 1

Troyanskaya Laboratory - Princeton University