ASD

GO:0035116 embryonic hindlimb morphogenesis (25)

GeneInput weightStandardRank
LRP6--279
RARB0.251300
CHD7--1416
DICER1--1762
SMARCA4--801
MED1--1034
GNAS--11842
NOTCH1--12865
ALX3--4288
WNT3--4613
RSPO2--4631
FGF4--4938
MECOM--4979
OSR1--5691
ALX4--5932
BMP4--16499
WNT7A--7312
MMP13--17779
GPC3--18430
RARG0.2518575
CTNNB10.519066
SHH--118571
OSR2--20931
RPGRIP1L--21472
PITX10.25121646

Network

GO:0035116

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
RARBretinoic acid receptor, beta Entrez:5915  HPRD: 07183  Ensembl: ENSG00000077092  HGNC: 9865 
CHD7chromodomain helicase DNA binding protein 7 Entrez:55636  Ensembl: ENSG00000171316  HGNC: 20626  HPRD: 10595 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Entrez:6597  HPRD: 04459  HGNC: 11100  Ensembl: ENSG00000127616 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
RARBretinoic acid receptor, beta
CHD7chromodomain helicase DNA binding protein 7
DICER1dicer 1, ribonuclease type III
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
RARBRARBretinoic acid receptor, beta
CHD7CHD7chromodomain helicase DNA binding protein 7
DICER1DICER1dicer 1, ribonuclease type III
SMARCA4SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Troyanskaya Laboratory - Princeton University