ASD

GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway (8)

GeneInput weightStandardRank
SPRY2--1454
WNT5A--3319
SULF1--4485
NGFR0.2516212
SULF2--8664
SPRY1--10636
WNT4--21809
THBS1--24444

Network

GO:0040037

Network
Enrichment
NameDescriptionExternal IDs
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
SULF1sulfatase 1 Entrez:23213  HGNC: 20391  HPRD: 15450  Ensembl: ENSG00000137573 
NGFRnerve growth factor receptor Entrez:4804  HGNC: 7809  HPRD: 01197  Ensembl: ENSG00000064300 
SULF2sulfatase 2 Entrez:55959  Ensembl: ENSG00000196562  HGNC: 20392  HPRD: 18130 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SPRY2sprouty homolog 2 (Drosophila)
WNT5Awingless-type MMTV integration site family, member 5A
SULF1sulfatase 1
NGFRnerve growth factor receptor
SULF2sulfatase 2
Query geneGeneGene descriptionEdge score
SPRY2SPRY2sprouty homolog 2 (Drosophila)
WNT5AWNT5Awingless-type MMTV integration site family, member 5A
SULF1SULF1sulfatase 1
NGFRNGFRnerve growth factor receptor
SULF2SULF2sulfatase 2

Troyanskaya Laboratory - Princeton University