ASD

GO:0050803 regulation of synapse structure and activity (38)

GeneInput weightStandardRank
SNAP250.25126
SLIT1--61
ADNP1.0171
NEUROD2--98
NCAN--206
ASIC20.251207
NLGN10.251276
GRIN1--294
MEF2C0.251428
CTNNA2--954
ROBO2--11202
APP--1515
SYNDIG1--1589
UBE2V2--1939
GHSR0.2512467
PTK20.2512488
FRMPD4--2763
NLGN31.012829
MEF2A--2837
WNT5A--3319
CYP19A10.2513823
MUSK--4006
PVRL1--4430
ANAPC2--5008
PTPRF--5040
NLGN2--5147
AGRN0.2516010
OXTR0.516388
WNT7A--7312
GHRL0.2519242
OXT0.25111176
PDLIM5--11350
THBS2--13069
PPT1--113834
ARHGEF15--15322
CHRNB20.25120216
KLK8--22593
CDC20--25608

Network

GO:0050803

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
NCANneurocan Entrez:1463  HGNC: 2465  HPRD: 02897  Ensembl: ENSG00000130287 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
SLIT1slit homolog 1 (Drosophila)
ADNPactivity-dependent neuroprotector homeobox
NEUROD2neuronal differentiation 2
NCANneurocan
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
SLIT1SLIT1slit homolog 1 (Drosophila)
ADNPADNPactivity-dependent neuroprotector homeobox
NEUROD2NEUROD2neuronal differentiation 2
NCANNCANneurocan

Troyanskaya Laboratory - Princeton University