ASD

GO:0090179 planar cell polarity pathway involved in neural tube closure (7)

GeneInput weightStandardRank
VANGL2--1793
DVL3--2090
WNT5A--3319
DVL2--6546
GRHL3--7409
DVL1P1--18731
DVL1--18924

Network

GO:0090179

Network
Enrichment
NameDescriptionExternal IDs
VANGL2VANGL planar cell polarity protein 2 Entrez:57216  Ensembl: ENSG00000162738  HGNC: 15511  HPRD: 02758 
DVL3dishevelled segment polarity protein 3 Entrez:1857  Ensembl: ENSG00000161202  HGNC: 3087  HPRD: 03222 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
DVL2dishevelled segment polarity protein 2 Entrez:1856  Ensembl: ENSG00000004975  HPRD: 03690  HGNC: 3086 
GRHL3grainyhead-like 3 (Drosophila) Entrez:57822  Ensembl: ENSG00000158055  HPRD: 12210  HGNC: 25839 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
VANGL2VANGL planar cell polarity protein 2
DVL3dishevelled segment polarity protein 3
WNT5Awingless-type MMTV integration site family, member 5A
DVL2dishevelled segment polarity protein 2
GRHL3grainyhead-like 3 (Drosophila)
Query geneGeneGene descriptionEdge score
VANGL2VANGL2VANGL planar cell polarity protein 2
DVL3DVL3dishevelled segment polarity protein 3
WNT5AWNT5Awingless-type MMTV integration site family, member 5A
DVL2DVL2dishevelled segment polarity protein 2
GRHL3GRHL3grainyhead-like 3 (Drosophila)

Troyanskaya Laboratory - Princeton University