ASD

GO:0045786 negative regulation of cell cycle (217)

GeneInput weightStandardRank
KHDRBS1--159
SOX2--1200
ADCYAP1--230
BRINP1--239
APC0.251266
GAS7--398
CUL1--478
DGKZ--547
BRINP2--576
MYO160.251691
MACF1--715
TSC10.251790
CAB39--797
SMARCA4--801
SMAD3--823
TGFB2--834
PTPRK--850
MAP2K10.251907
APBB2--930
BRINP3--1077
DST--1092
CUL31.011093
TSPYL2--1106
BMP7--1137
CDKN1B--1162
KMT2E0.511234
TPR--1243
PTEN1.011389
HDAC2--1440
WNT10B--1517
BUB3--1718
CDK6--1795
RPRM--1866
PPP1R15A--2011
PRKAB2--2067
PPM1A--2070
CUL2--2097
TP53INP1--2121
CDC123--2169
USP47--2202
PPP2R5B--2296
CUL5--2323
GATA3--2376
EIF4G2--2453
TP53BP2--2477
BCL6--2550
CDKN2D--2582
FGFR3--12640
PDCD4--2707
LATS1--2781
SKIL--2889
CDKN1C--12938
NR2F2--2941
APBB1--3094
RHOB--3118
VASH10.2513148
PPP1R9B--3166
CDK50.2513194
HBP1--3343
CHMP1A--3372
USP44--3406
TCF7L20.513548
IL12B--3596
UHMK1--3601
ATM--13622
RHEB--3728
DLG1--3822
PRKAA2--3894
BTG4--3954
PRKAG2--14212
SESN1--4365
WNT1--4383
PTPN3--4627
INHA--4765
TERF1--4825
BMP2--14855
MEN1--14917
C2orf40--5001
ANAPC2--5008
HRAS0.2515086
WDR6--5182
GADD45A--5185
BARD1--15343
PRNP--15418
IFNW1--5500
JMY--5725
TAF6--5876
MYOCD--5907
CGREF1--5934
ETS1--5943
HEXIM1--5982
STK11--16000
NGFR0.2516212
NGF0.2516229
MSH2--16311
RUNX3--6322
STRADA--6362
TFAP4--6377
BMP4--16499
PCBP4--6634
MAD1L1--16635
NOTCH2--16664
ZBTB17--6799
RB1--16804
BTG3--6884
GAS1--6937
GAS2--7008
ILK--7305
PPP1R13B--7576
CDKN1A--7714
TBRG1--7747
SESN2--7868
UBE2E1--7950
PRDM4--8037
GAS2L1--8911
TSC20.2519351
FOXO4--9362
CREB3--9450
PRKACA--9630
CDC27--9665
LATS2--9736
MTBP--9879
ERN1--9939
SESN3--10241
PRKAG3--10274
MAP2K6--10478
IL12A--10482
CAB39L--10629
HEPACAM0.25110771
TSG101--110967
GAS2L2--11077
DCUN1D3--11179
RBM38--11401
PSMG2--12810
HDAC1--12825
IFNG--112827
TRIM35--12958
PPM1G--13184
THAP5--13300
FOXC1--113793
MAD2L2--13802
PLAGL1--13916
RNF167--14002
AURKAIP1--14217
RPTOR--14284
CDC23--14728
CDKN2B--14806
DDIT3--14883
ANAPC11--14928
CGRRF1--15792
IL8--15864
NBN--116066
INHBA--16974
GAS2L3--17383
TP530.25118277
TP73--18810
TGFB10.25120135
SGSM3--20539
CDKN2A--120587
PPP2R3B--20597
SART1--20962
ANAPC10--21179
ING4--21206
SIPA1--21260
MAPK12--21269
DHCR24--21358
CYP27B1--21369
HEXIM2--21545
MLF1--21547
PRKAB1--21601
ILKAP--21650
HDAC3--21702
CALR--22152
RASSF1--22228
CDC26--22265
HPGD--122284
MYC--122615
PRKAA1--22917
HNF4A--122965
IRF6--122999
TBRG4--23190
STRADB--23510
KAT2B--23529
AIF1--23667
SCRIB--23676
PLA2G16--23769
CRLF3--23856
COMMD5--24048
CDKN2C--24062
BUB1--24227
CUL4A--24230
PRKAG1--24404
ANAPC4--24419
THBS1--24444
ALOX15B--24590
ANAPC7--24632
CDK5RAP1--24649
GMNN--24671
C11orf82--24676
AK1--124761
NME6--24901
UBE2D1--24988
CDC16--24989
KIF20B--25182
ANAPC1--25203
PNPT1--25216
PML--25277
MAD2L1--25321
ANAPC5--25367
CENPF--25495
CDKN3--25528
CDC20--25608
UBE2C--25614
TTK--25648
PA2G4--25687
BUB1B--125766
PLK1--25783

Network

GO:0045786

Network
Enrichment
NameDescriptionExternal IDs
KHDRBS1KH domain containing, RNA binding, signal transduction associated 1 Entrez:10657  HGNC: 18116  Ensembl: ENSG00000121774  HPRD: 03926 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) Entrez:116  HGNC: 241  HPRD: 02369  Ensembl: ENSG00000141433 
BRINP1bone morphogenetic protein/retinoic acid inducible neural-specific 1 Entrez:1620  HPRD: 04181  Ensembl: ENSG00000078725  HGNC: 2687 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KHDRBS1KH domain containing, RNA binding, signal transduction associated 1
SOX2SRY (sex determining region Y)-box 2
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
BRINP1bone morphogenetic protein/retinoic acid inducible neural-specific 1
APCadenomatous polyposis coli
Query geneGeneGene descriptionEdge score
KHDRBS1KHDRBS1KH domain containing, RNA binding, signal transduction associated 1
SOX2SOX2SRY (sex determining region Y)-box 2
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
BRINP1BRINP1bone morphogenetic protein/retinoic acid inducible neural-specific 1
APCAPCadenomatous polyposis coli

Troyanskaya Laboratory - Princeton University