ASD

GO:0014741 negative regulation of muscle hypertrophy (8)

GeneInput weightStandardRank
AKAP1--4078
GSK3A--4141
MSTN--4329
RGS2--5095
BMP10--5102
CAV3--115414
P2RX4--22325
GLRX3--25135

Network

GO:0014741

Network
Enrichment
NameDescriptionExternal IDs
AKAP1A kinase (PRKA) anchor protein 1 Entrez:8165  Ensembl: ENSG00000121057  HPRD: 03905  HGNC: 367 
GSK3Aglycogen synthase kinase 3 alpha Entrez:2931  HGNC: 4616  HPRD: 06002  Ensembl: ENSG00000105723 
MSTNmyostatin Entrez:2660  HPRD: 03474  Ensembl: ENSG00000138379  HGNC: 4223 
RGS2regulator of G-protein signaling 2, 24kDa Entrez:5997  HGNC: 9998  HPRD: 02917  Ensembl: ENSG00000116741 
BMP10bone morphogenetic protein 10 Entrez:27302  Ensembl: ENSG00000163217  HPRD: 09788  HGNC: 20869 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AKAP1A kinase (PRKA) anchor protein 1
GSK3Aglycogen synthase kinase 3 alpha
MSTNmyostatin
RGS2regulator of G-protein signaling 2, 24kDa
BMP10bone morphogenetic protein 10
Query geneGeneGene descriptionEdge score
AKAP1AKAP1A kinase (PRKA) anchor protein 1
GSK3AGSK3Aglycogen synthase kinase 3 alpha
MSTNMSTNmyostatin
RGS2RGS2regulator of G-protein signaling 2, 24kDa
BMP10BMP10bone morphogenetic protein 10

Troyanskaya Laboratory - Princeton University