ASD

GO:0051961 negative regulation of nervous system development (5)

GeneInput weightStandardRank
SLIT1--61
ROBO2--11202
PTK20.2512488
WNT5A--3319
WNT8B--3407

Network

GO:0051961

Network
Enrichment
NameDescriptionExternal IDs
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila) Entrez:6092  HGNC: 10250  Ensembl: ENSG00000185008 
PTK2protein tyrosine kinase 2 Entrez:5747  HPRD: 02859  HGNC: 9611  Ensembl: ENSG00000169398 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
WNT8Bwingless-type MMTV integration site family, member 8B Entrez:7479  HGNC: 12789  HPRD: 03235  Ensembl: ENSG00000075290 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT1slit homolog 1 (Drosophila)
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)
PTK2protein tyrosine kinase 2
WNT5Awingless-type MMTV integration site family, member 5A
WNT8Bwingless-type MMTV integration site family, member 8B
Query geneGeneGene descriptionEdge score
SLIT1SLIT1slit homolog 1 (Drosophila)
ROBO2ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)
PTK2PTK2protein tyrosine kinase 2
WNT5AWNT5Awingless-type MMTV integration site family, member 5A
WNT8BWNT8Bwingless-type MMTV integration site family, member 8B

Troyanskaya Laboratory - Princeton University