ASD

GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway (7)

GeneInput weightStandardRank
DRD10.251899
DRD50.2511103
GNAL--1177
GNAS--11842
ADCY5--4295
DRD30.2514349
SLC9A3R1--21898

Network

GO:0007191

Network
Enrichment
NameDescriptionExternal IDs
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
GNASGNAS complex locus Entrez:2778  HGNC: 4392  HPRD: 00761  Ensembl: ENSG00000087460 
ADCY5adenylate cyclase 5 Entrez:111  Ensembl: ENSG00000173175  HGNC: 236  HPRD: 08973 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DRD1dopamine receptor D1
DRD5dopamine receptor D5
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNASGNAS complex locus
ADCY5adenylate cyclase 5
Query geneGeneGene descriptionEdge score
DRD1DRD1dopamine receptor D1
DRD5DRD5dopamine receptor D5
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNASGNASGNAS complex locus
ADCY5ADCY5adenylate cyclase 5

Troyanskaya Laboratory - Princeton University