ASD

GO:0051960 regulation of nervous system development (338)

GeneInput weightStandardRank
NTRK30.2516
SNAP250.25126
CNR10.25129
BCL11A1.0132
NTRK20.25151
SLIT1--61
TTC3--68
NRCAM0.25169
ADNP1.0171
PAFAH1B10.25174
MAPT0.25176
SOX11--96
NEUROD2--98
ARHGDIA--109
NEUROD1--1127
SYNJ1--156
CDH2--164
SOX2--1200
ASIC20.251207
GRM50.251240
CACNA1A--1270
NLGN10.251276
LRP6--279
GRIN1--294
SEMA4F--303
EP300--1318
RAP2A--324
DSCAM1.01330
TCF4--337
STMN2--343
NF10.251372
DBN1--385
ATN1--1402
MAP1B--403
ASCL1--413
NREP--417
SALL1--506
RET--1524
EPHA3--532
PAX60.251544
SPAG9--558
CDK5R1--586
OLIG2--619
PAX2--653
SLIT2--659
FOXG1--661
CNTN2--674
SIPA1L1--716
POU3F2--750
DICER1--1762
IL1RAPL10.251774
CCND2--782
BDNF0.251791
ACTR3--803
RGS6--805
OMG0.251808
CDH4--812
ZNF536--839
DLL3--1847
RAPGEF40.251904
RUFY3--906
CHRD--941
SOX9--1970
NR2E10.251977
ULK1--1008
ID4--1009
AKT10.2511020
NDEL10.2511074
NKX2-2--1120
BMP7--1137
BMPR1A--1140
RELA--1142
MIB10.2511153
HOXD3--1195
ROBO2--11202
ZHX2--1216
DISC10.511238
CHRNA3--1266
PTEN1.011389
HDAC2--1440
APP--1515
SOX10--11520
TNIK--1531
XRCC5--1550
THY1--1580
SYNDIG1--1589
DCC--1687
LZTS1--11709
SRCIN1--1738
AKAP5--1759
VANGL2--1793
LRRC4C--1827
YWHAG--1857
SMAD1--1872
ZEB1--11901
PHOX2B--1917
UBE2V2--1939
ISL1--1974
FOXA1--1990
YWHAH--2009
ACHE--2025
EDNRB--12042
DLL1--2053
XYLT1--12057
DVL3--2090
MBP--2120
ID2--2154
SSH2--2172
ROBO1--2182
RNF6--12235
FGFR1--2262
KIAA0319--2279
MARK2--2280
GDF6--12291
RHOA--2292
PPP2R5B--2296
SOX3--2303
CIT--2320
DLX20.2512357
STK25--2375
DLX10.2512400
CAPRIN1--2429
GHSR0.2512467
GFAP--12475
PTK20.2512488
CNTN41.012492
SOX21--2559
LHX1--2560
NCS1--2628
FGFR3--12640
FOXA2--2645
DPYSL2--2672
MYRF--2677
RTN4--2735
SHOX2--2767
TULP3--2770
IGF10.2512793
NRP1--2807
NLGN31.012829
PLXNB1--2853
NOTCH1--12865
SKIL--2889
SKI--2904
NEUROG2--2989
FEZ1--3035
PTK2B--3063
HOOK3--3126
KNDC1--3146
MT3--3160
TGIF2--3180
NPTN--3227
NTF30.2513232
TGIF1--13264
ARF6--3317
WNT5A--3319
WNT8B--3407
CDON--3487
SEMA3A--3494
CCDC88A--3536
CDKL5--13600
NUMBL--3618
INPP5J--3690
SERPINE2--3708
DIXDC1--3734
DRD20.2513749
TNR--3868
ITGB1--3903
LHX5--3998
MUSK--4006
TSPO0.2514009
SSH1--4066
ITM2C--4102
GDF11--4104
SLC6A40.2514137
LPAR1--4170
LMX1A--4236
LIMK1--4265
HOXA2--4273
CAPRIN2--4284
DRD30.2514349
BMP6--4358
ZNF488--4377
NDNF--4408
PVRL1--4430
BARHL2--4545
SOX8--4609
WNT3--4613
NEUROG10.2514644
NKX6-1--4665
INPPL1--4681
WNT3A--4747
NKX6-2--4791
INPP5E--4823
BMP2--14855
HES5--4919
DYNLT1--4976
ANAPC2--5008
PTPRF--5040
NLGN2--5147
DTX1--5290
RYK--5383
PLXNA4--5391
CXCR4--5414
NOG--15439
OTP--5490
ASPA--15501
MAG--5765
HES10.2515912
STK11--16000
AGRN0.2516010
NTN1--6023
TLX2--6047
LGALS1--6065
NGFR0.2516212
NGF0.2516229
GLI3--16261
RTN4R--6304
LINGO1--6321
OXTR0.516388
TCF3--6420
TLX3--6462
BMP4--16499
DVL2--6546
PCM1--16569
GDF7--6682
ISLR2--7030
LIN28A--7070
LIG4--17187
ILK--7305
WNT7A--7312
GRHL3--7409
VAX1--7419
HES3--7466
IRX3--7476
CXCL12--7802
NUMB--7848
AVIL--7943
MET1.018002
ABL2--8082
FRMD7--8376
NKX2-50.2518486
ADRA2C--8551
KATNB1--8593
LRRK2--18802
VWC2--8879
CTNNB10.519066
LBX1--9134
GHRL0.2519242
CTNNA1--9331
NBL1--9632
REST--9779
TRIM320.2519794
SCARF1--9851
ADRA2B--10119
ASCL2--10237
ACE--10304
LYN--10336
NEUROG3--10352
FIG4--110446
SMO0.25110504
XRCC2--10672
OXT0.25111176
ATOH1--11336
PDLIM5--11350
RHOC--11655
PLXNB2--12091
SIX1--112393
SPP1--12442
HEYL--12571
IL6--112695
SEMA4D--12699
IFNG--112827
VEGFC--12850
EGF0.25112881
RGS14--12999
THBS2--13069
FGF2--13150
PTK7--13643
SEMA7A--13700
PMP22--113921
NEDD40.25114040
TRIM11--14084
KATNA1--14335
KIF13B--14390
DNMT3B--14663
PTK6--14914
ARHGEF15--15322
PLK5--15898
TRPV4--115988
FEZF10.25116009
NBN--116066
PSEN1--18523
TG--18556
SHH--118571
F2--118599
DGUOK--18662
DVL1P1--18731
TP73--18810
DVL1--18924
METRN--19614
LTK--19737
TGFB10.25120135
CHRNB20.25120216
EPO--20282
EIF2AK3--20456
AMIGO1--20613
TTL--20764
CLCF1--21194
ARHGEF1--21297
CDK5RAP2--121330
EFNA1--21477
CTDSP1--21639
NOTCH3--22114
LIF--22134
CALR--22152
RNF10--22383
KLK8--22593
PPARG--122729
XRCC6--22834
TNFRSF12A--22985
PRPF19--22991
TWF2--23010
CCL5--23042
APOE0.25123516
FKBP4--23829
TIMP2--23892
SSH3--23947
P2RY2--24088
TRPV2--24139
ATF5--24234
ATF1--24277
CDK5RAP3--24423
CDK5RAP1--24649
ASPM--124942
SERPINF1--25093
XRCC4--25256
FXN--125604
CDC20--25608

Network

GO:0051960

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) Entrez:53335  Ensembl: ENSG00000119866  HGNC: 13221  HPRD: 05949 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
SNAP25synaptosomal-associated protein, 25kDa
CNR1cannabinoid receptor 1 (brain)
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
NTRK2neurotrophic tyrosine kinase, receptor, type 2
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
SNAP25SNAP25synaptosomal-associated protein, 25kDa
CNR1CNR1cannabinoid receptor 1 (brain)
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2

Troyanskaya Laboratory - Princeton University