ASD

GO:0043623 cellular protein complex assembly (179)

GeneInput weightStandardRank
SYNJ1--156
AP2S1--210
GRIK20.51232
MAGI2--255
CACNA1A--1270
DLG20.251328
GAS7--398
TCP1--412
MAPK8IP2--418
POGZ1.01514
SNAP91--546
ADRM1--611
HSP90AA1--727
TUBB3--729
GRIN2B1.01763
ZFYVE9--795
SMAD4--821
SMAD3--823
TUBB4A--854
DLG4--857
NRG10.251936
WASF3--1046
TUBB4B--1087
CSNK2B--1126
CHRNA3--1266
FKBP1A--1284
NDUFS8--11294
PRLR0.2511393
GRIK5--1396
LRP4--1500
WASF1--1544
RAC1--1617
TUBB2A--1641
HIP1--1797
SMAD1--1872
TPPP--1992
UBE2S--2043
TUBB2B--2184
POMP--2205
PSMD10--2412
CALY--2456
PTK20.2512488
TUBA1B--2576
PICALM--12597
SMAD2--2694
PREX1--2760
TUBB--2800
SRC--2825
ARPC4--2880
PTK2B--3063
NCK2--3077
ALDOB--3137
CDK50.2513194
TUBG2--3864
MUSK--4006
APCS--4060
ANGPT1--4182
TBCA--4248
FLNA--14285
AXIN1--14419
MBD2--4518
TUBB7P--4739
WNT3A--4747
TTC19--4799
HSPD1--14908
EPS15--5197
AHCTF1--5306
NDUFS7--15324
ARHGAP6--5374
ARL6--15581
TTN--15620
TUBA1C--5722
TUBA8--5891
ARL2--5930
AGRN0.2516010
CRP--6053
C9orf24--6156
DNAAF1--16308
PDGFC--6530
TGFBR3--6672
PXN--6823
TUBA1A--16849
PDE4DIP--6923
TUBA4A--7023
THEG--7092
CYBA--17322
PILRB--7462
KIF13A--7474
HSPA4--7593
NUP98--7869
MC1R--17999
ANLN--8838
NLRP5--8904
TUBAL3--8928
MID1IP1--9080
LONP1--9137
CCDC39--9326
FGA--19461
FGB--19587
CD3E--9680
TUBE1--10209
SMO0.25110504
CRYAA--10509
SCO2--111242
PICK1--11315
TUBB1--11749
CCDC40--11931
NUP205--12777
PSMG2--12810
NCK1--12890
UNC13B--13412
OOEP--13495
PSMD9--13911
NDUFS5--13997
FGG--15642
TRPV4--115988
DVL1P1--18731
SRP54--18826
NDUFAF5--18845
DVL1--18924
JAK2--119561
TUBA3D--19646
PSMD5--19823
TGFB10.25120135
CENPJ--120337
TUBD1--20600
TUBG1--20656
SURF1--120914
TUBA3E--20921
TMEM70--20936
NDUFAF3--21155
CCT6B--21264
VMA21--21374
EID2--21599
TCAP--122131
CALR--22152
NDUFAF7--22163
VIL10.5122243
COX11--22335
TUBA4B--22642
TFAM--22756
NDUFS4--122766
CCL5--23042
NUBPL--23231
ADRB20.25123251
COX18--23354
ATPAF2--23361
TUBA3C--23436
MYH11--123442
COX10--23489
FMOD--23581
SDHAF1--23629
TRAF2--23686
COG4--123743
DNAAF2--123949
GSN--124007
MSTO1--24077
MIS12--24173
TUBB6--24179
ATF1--24277
PEX13--124461
WAS--124487
ANG--124879
CRYAB--124965
TAZ--124981
NDUFAF4--25049
PSMG1--25073
COX15--125238
PFDN6--25409
FBXO5--25488
CENPF--25495
MLH1--125513
UBE2C--25614
SCO1--25694
OXA1L--25710
CENPE--25732
CENPA--25744
NDC1--25806
BCS1L--125825

Network

GO:0043623

Network
Enrichment
NameDescriptionExternal IDs
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
AP2S1adaptor-related protein complex 2, sigma 1 subunit Entrez:1175  HPRD: 03762  Ensembl: ENSG00000042753  HGNC: 565 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 Entrez:9863  Ensembl: ENSG00000187391  HGNC: 18957  HPRD: 16212 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYNJ1synaptojanin 1
AP2S1adaptor-related protein complex 2, sigma 1 subunit
GRIK2glutamate receptor, ionotropic, kainate 2
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Query geneGeneGene descriptionEdge score
SYNJ1SYNJ1synaptojanin 1
AP2S1AP2S1adaptor-related protein complex 2, sigma 1 subunit
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
MAGI2MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Troyanskaya Laboratory - Princeton University