ASD

GO:0017148 negative regulation of translation (45)

GeneInput weightStandardRank
FMR10.251434
AGO2--490
TSC10.251790
TNRC6A--1752
AGO3--2124
NDUFA13--12204
FXR1--2395
CAPRIN1--2429
CIRBP--2440
TIA1--2578
AGO1--2764
PAIP2--3171
IGFBP5--3306
AGO4--3370
RARA0.2513695
SRP9--3762
RBM4--4069
CAPRIN2--4284
WT1--14514
SAMD4A--4734
IGF2BP1--6258
PAIP2B--6933
EIF4A3--7597
YBX2--8277
IGF2BP2--19556
NANOS1--10456
PRG3--10802
IGF2BP3--11232
EIF4EBP2--14825
PATL2--19573
EIF2AK3--20456
GRB7--20514
EIF2AK4--21300
EIF4EBP3--21431
CALR--22152
EIF4EBP1--22803
GNB2L1--23282
SRP14--23614
EIF2AK1--23647
EIF2B4--24428
ANG--124879
EIF3E--25133
PML--25277
EIF2B5--25325
EIF2B3--25449

Network

GO:0017148

Network
Enrichment
NameDescriptionExternal IDs
FMR1fragile X mental retardation 1 Entrez:2332  Ensembl: ENSG00000102081  HPRD: 02398  HGNC: 3775 
AGO2argonaute RISC catalytic component 2 Entrez:27161  HGNC: 3263  HPRD: 06943  Ensembl: ENSG00000123908 
TSC1tuberous sclerosis 1 Entrez:7248  Ensembl: ENSG00000165699  HGNC: 12362  HPRD: 05594 
TNRC6Atrinucleotide repeat containing 6A Entrez:27327  HPRD: 11640  HGNC: 11969  Ensembl: ENSG00000090905 
AGO3argonaute RISC catalytic component 3 Entrez:192669  HGNC: 18421  HPRD: 09558  Ensembl: ENSG00000126070 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FMR1fragile X mental retardation 1
AGO2argonaute RISC catalytic component 2
TSC1tuberous sclerosis 1
TNRC6Atrinucleotide repeat containing 6A
AGO3argonaute RISC catalytic component 3
Query geneGeneGene descriptionEdge score
FMR1FMR1fragile X mental retardation 1
AGO2AGO2argonaute RISC catalytic component 2
TSC1TSC1tuberous sclerosis 1
TNRC6ATNRC6Atrinucleotide repeat containing 6A
AGO3AGO3argonaute RISC catalytic component 3

Troyanskaya Laboratory - Princeton University