ASD

GO:0001704 formation of primary germ layer (60)

GeneInput weightStandardRank
SOX2--1200
BMPR2--1281
PAX2--653
SMAD3--823
CHRD--941
NR4A3--1963
BMP7--1137
BMPR1A--1140
LEF1--1499
SMAD1--1872
DUSP5--2022
EPB41L5--2335
PRKAR1A--12428
LHX1--2560
FOXA2--2645
SMAD2--2694
SRF--2841
NODAL--13149
FOXF1--13518
HAND1--3590
KLF4--3609
DUSP1--3785
DUSP4--4019
SOX17--4024
NANOG--4083
AXIN1--14419
HOXA11--4432
WNT3--4613
WNT3A--4747
NF2--15991
TLX2--6047
ACVR1--16054
SOX7--6117
EYA2--6194
SIX2--6306
BMP4--16499
WNT8A--7814
DUSP2--8596
TBX20--18764
CTNNB10.519066
SNAI1--9198
PRKACA--9630
TDGF1P3--9765
MIXL1--9839
FOXC2--10175
EOMES--12952
FOXC1--113793
MESP1--13805
WLS--15707
INHBA--16974
EPHA2--119467
POU5F1--19704
FOXS1--20143
TXNRD1--20757
TRIM15--21614
ECSIT--22627
MESP2--122723
KIF16B--22922
TWSG1--24840
EXT2--125243

Network

GO:0001704

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PAX2paired box 2
SMAD3SMAD family member 3
CHRDchordin
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
PAX2PAX2paired box 2
SMAD3SMAD3SMAD family member 3
CHRDCHRDchordin

Troyanskaya Laboratory - Princeton University