ASD

GO:0090031 positive regulation of steroid hormone biosynthetic process (6)

GeneInput weightStandardRank
IGF1R--252
CYP17A10.2513984
BMP6--4358
POR0.2515184
WNT4--21809
IGF20.25122401

Network

GO:0090031

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1 Entrez:1586  HPRD: 01944  Ensembl: ENSG00000148795  HGNC: 2593 
BMP6bone morphogenetic protein 6 Entrez:654  Ensembl: ENSG00000153162  HGNC: 1073  HPRD: 00211 
PORP450 (cytochrome) oxidoreductase Entrez:5447  HGNC: 9208  Ensembl: ENSG00000127948  HPRD: 00485 
WNT4wingless-type MMTV integration site family, member 4 Entrez:54361  HGNC: 12783  Ensembl: ENSG00000162552  HPRD: 04601 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1
BMP6bone morphogenetic protein 6
PORP450 (cytochrome) oxidoreductase
WNT4wingless-type MMTV integration site family, member 4
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
CYP17A1CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1
BMP6BMP6bone morphogenetic protein 6
PORPORP450 (cytochrome) oxidoreductase
WNT4WNT4wingless-type MMTV integration site family, member 4

Troyanskaya Laboratory - Princeton University