ASD

GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (32)

GeneInput weightStandardRank
SMG1--579
DCP2--713
ETF1--832
CTIF--1664
UPF2--1986
UPF1--2170
PAN3--2201
CASC3--2246
MAGOH--2595
RBM8A--12710
DCP1A--2719
SMG7--2731
PNRC2--2847
RNPS1--2983
SMG5--4156
SMG6--5225
UPF3A--5542
GSPT1--6042
EIF4A3--7597
GSPT2--7624
PAN2--10916
SMG9--12600
UPF3B--21339
DCP1B--22040
EXOSC10--22236
SMG8--22541
NCBP2--23216
DCPS--24092
WIBG--24922
EIF3E--25133
PARN--25199
NCBP1--25523

Network

GO:0000184

Network
Enrichment
NameDescriptionExternal IDs
SMG1SMG1 phosphatidylinositol 3-kinase-related kinase Entrez:23049  HPRD: 06123  HGNC: 30045  Ensembl: ENSG00000157106 
DCP2decapping mRNA 2 Entrez:167227  HPRD: 13125  Ensembl: ENSG00000172795  HGNC: 24452 
ETF1eukaryotic translation termination factor 1 Entrez:2107  Ensembl: ENSG00000120705  HGNC: 3477  HPRD: 02616 
CTIFCBP80/20-dependent translation initiation factor Entrez:9811  Ensembl: ENSG00000134030  HGNC: 23925  HPRD: 11083 
UPF2UPF2 regulator of nonsense transcripts homolog (yeast) Entrez:26019  HGNC: 17854  Ensembl: ENSG00000151461  HPRD: 10405 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMG1SMG1 phosphatidylinositol 3-kinase-related kinase
DCP2decapping mRNA 2
ETF1eukaryotic translation termination factor 1
CTIFCBP80/20-dependent translation initiation factor
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)
Query geneGeneGene descriptionEdge score
SMG1SMG1SMG1 phosphatidylinositol 3-kinase-related kinase
DCP2DCP2decapping mRNA 2
ETF1ETF1eukaryotic translation termination factor 1
CTIFCTIFCBP80/20-dependent translation initiation factor
UPF2UPF2UPF2 regulator of nonsense transcripts homolog (yeast)

Troyanskaya Laboratory - Princeton University