ASD

GO:0030073 insulin secretion (26)

GeneInput weightStandardRank
NEUROD1--1127
RIMS2--282
CAMK2G--798
RAPGEF40.251904
ACVR2B--11676
VGF0.2511782
FKBP1B--2346
SMAD2--2694
CPLX1--2778
SLC30A8--13644
MC4R0.2513850
CPLX3--4281
SLC18A2--6423
PDX1--17958
HNF1B--19881
CCKAR--11747
FAM3B--12628
MAFA--13014
GPR119--13402
GAL--13897
DGAT1--14036
HNF1A--114631
EIF2AK3--20456
CYB5R4--20918
ANXA10.5122810
IL1RN0.25125385

Network

GO:0030073

Network
Enrichment
NameDescriptionExternal IDs
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
RIMS2regulating synaptic membrane exocytosis 2 Entrez:9699  HGNC: 17283  HPRD: 09436 
CAMK2Gcalcium/calmodulin-dependent protein kinase II gamma Entrez:818  HPRD: 03672  Ensembl: ENSG00000148660  HGNC: 1463 
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 Entrez:11069  Ensembl: ENSG00000091428  HGNC: 16626  HPRD: 06929 
ACVR2Bactivin A receptor, type IIB Entrez:93  HGNC: 174  HPRD: 04106 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NEUROD1neuronal differentiation 1
RIMS2regulating synaptic membrane exocytosis 2
CAMK2Gcalcium/calmodulin-dependent protein kinase II gamma
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
ACVR2Bactivin A receptor, type IIB
Query geneGeneGene descriptionEdge score
NEUROD1NEUROD1neuronal differentiation 1
RIMS2RIMS2regulating synaptic membrane exocytosis 2
CAMK2GCAMK2Gcalcium/calmodulin-dependent protein kinase II gamma
RAPGEF4RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
ACVR2BACVR2Bactivin A receptor, type IIB

Troyanskaya Laboratory - Princeton University