ASD

GO:0006417 regulation of translation (168)

GeneInput weightStandardRank
PUM2--1
PUM1--10
QKI--18
LSM14A--103
TNRC6B0.51145
SOX4--250
EP300--1318
EIF5--323
FMR10.251434
AGO2--490
APLP1--591
DIO2--625
CPEB2--767
TSC10.251790
ETF1--832
AKT10.2511020
DDX25--1069
EIF4G3--1083
MAPK1--1128
DDX1--1332
ATXN2--11422
APP--1515
RPS6KB1--1521
CTIF--1664
PAIP1--1686
TNRC6A--1752
PPP1R15A--2011
CPEB1--2015
AGO3--2124
UPF1--2170
NDUFA13--12204
CASC3--2246
FXR1--2395
MTPN--2402
CAPRIN1--2429
CIRBP--2440
EIF4G2--2453
EIF4A2--2547
TIA1--2578
MAGOH--2595
RBM8A--12710
AGO1--2764
EIF4E3--2819
EIF4H--3011
PTK2B--3063
NCK2--3077
ZFP36L1--3125
PAIP2--3171
IGFBP5--3306
AGO4--3370
EIF4G1--3374
TNRC6C--3423
UHMK1--3601
RARA0.2513695
SRP9--3762
EIF1--3852
METAP1--4059
RBM4--4069
CAPRIN2--4284
EIF4E0.2514457
WT1--14514
BARHL2--4545
SAMD4A--4734
PIWIL2--4828
RGS2--5095
UPF3A--5542
PIWIL1--5575
MKNK2--5595
IGF2BP1--6258
DAZ1--6267
MAPK30.2516426
CD28--6931
PAIP2B--6933
DAZL--7043
LIN28A--7070
PPP1R15B--7177
EIF4A3--7597
BCL3--7998
POLDIP3--8198
YBX2--8277
EIF4E2--8852
BOLL--8978
PIWIL4--8984
GATC--9108
PABPC1--9200
EIF2S1--9361
IGF2BP2--19556
UCN--10358
NANOS2--10402
NANOS1--10456
EIF4E1B--10677
PRG3--10802
IGF2BP3--11232
EIF1B--11399
SERP1--11460
LSM14B--11537
RHOC--11655
SARNP--11742
RPS14--12584
EIF5A2--12630
IL6--112695
EIF5B--12882
NCK1--12890
FAM129A--13686
EIF4EBP2--14825
TNF0.25115243
NGDN--16655
NANOS3--16954
PSTK--18190
EIF3K--19178
PATL2--19573
PIWIL3--19948
EIF2AK3--20456
GRB7--20514
TRNAU1AP--20885
EIF2A--20947
MTOR--21095
EIF2AK4--21300
UPF3B--21339
EIF4EBP3--21431
SBDS--21769
CALR--22152
EIF4B--22190
SEPSECS--22373
MTRF1--22450
EIF5AL1--22509
RBM3--22670
EIF5A--22674
EIF4EBP1--22803
CCL5--23042
NCBP2--23216
RPS6KB2--23226
MIF4GD--23279
GNB2L1--23282
MKNK1--23294
HSPB1--123318
EIF2B1--23375
ABCF1--23393
SRP14--23614
EIF2AK1--23647
MTIF3--23826
DNAJC1--24415
EIF2B4--24428
IMPACT--24430
THBS1--24444
TACO1--24595
TARBP2--24667
EIF3B--24833
ANG--124879
MTIF2--24918
WIBG--24922
HRSP12--25020
EIF3E--25133
TRMT6--25175
RPS27L--25183
PML--25277
EIF2B5--25325
EIF3H--25335
EIF2B2--25351
GCN1L1--25355
KRT7--25386
EIF2B3--25449
ACO1--25454
RPS9--25509
NCBP1--25523
RPS4X--25564
PA2G4--25687
RPS5--25795

Network

GO:0006417

Network
Enrichment
NameDescriptionExternal IDs
PUM2pumilio RNA-binding family member 2 Entrez:23369  Ensembl: ENSG00000055917  HGNC: 14958  HPRD: 09527 
PUM1pumilio RNA-binding family member 1 Entrez:9698  Ensembl: ENSG00000134644  HGNC: 14957  HPRD: 06230 
QKIQKI, KH domain containing, RNA binding Entrez:9444  HPRD: 06691  Ensembl: ENSG00000112531  HGNC: 21100 
LSM14ALSM14A, SCD6 homolog A (S. cerevisiae) Entrez:26065  Ensembl: ENSG00000257103  HPRD: 12697  HGNC: 24489 
TNRC6Btrinucleotide repeat containing 6B Entrez:23112  Ensembl: ENSG00000100354  HGNC: 29190 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PUM2pumilio RNA-binding family member 2
PUM1pumilio RNA-binding family member 1
QKIQKI, KH domain containing, RNA binding
LSM14ALSM14A, SCD6 homolog A (S. cerevisiae)
TNRC6Btrinucleotide repeat containing 6B
Query geneGeneGene descriptionEdge score
PUM2PUM2pumilio RNA-binding family member 2
PUM1PUM1pumilio RNA-binding family member 1
QKIQKIQKI, KH domain containing, RNA binding
LSM14ALSM14ALSM14A, SCD6 homolog A (S. cerevisiae)
TNRC6BTNRC6Btrinucleotide repeat containing 6B

Troyanskaya Laboratory - Princeton University