ASD

GO:0051897 positive regulation of protein kinase B signaling cascade (41)

GeneInput weightStandardRank
IGF1R--252
SPRY2--1454
MTDH--1461
ITSN1--1789
GATA3--2376
EGFR--12546
IGF10.2512793
IGFBP5--3306
TSPYL5--3354
TCF7L20.513548
PDGFA--3731
NOX4--3804
HBEGF--3865
ANGPT1--4182
TNFSF11--15271
TEK--5322
F7--5465
RASD2--5562
INSR--15872
TGFBR1--17268
ILK--7305
MC1R--17999
PTPRJ--19136
ARRB2--10647
F3--10889
GPX10.25111644
IL26--11645
VEGFB--11980
IL6--112695
CCL19--14578
ZP3--17443
TGFB10.25120135
MTOR--21095
KIAA1161--21137
ADAM8--21797
CCL21--21829
INS--122047
F10--22126
CCR7--22367
IGF20.25122401
THBS1--24444

Network

GO:0051897

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
MTDHmetadherin Entrez:92140  Ensembl: ENSG00000147649  HGNC: 29608  HPRD: 17459 
ITSN1intersectin 1 (SH3 domain protein) Entrez:6453  HPRD: 03898  Ensembl: ENSG00000205726  HGNC: 6183 
GATA3GATA binding protein 3 Entrez:2625  HGNC: 4172  Ensembl: ENSG00000107485  HPRD: 00572 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
SPRY2sprouty homolog 2 (Drosophila)
MTDHmetadherin
ITSN1intersectin 1 (SH3 domain protein)
GATA3GATA binding protein 3
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
SPRY2SPRY2sprouty homolog 2 (Drosophila)
MTDHMTDHmetadherin
ITSN1ITSN1intersectin 1 (SH3 domain protein)
GATA3GATA3GATA binding protein 3

Troyanskaya Laboratory - Princeton University