ASD

GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger (12)

GeneInput weightStandardRank
DRD10.251899
CALCA--1013
DRD20.2513749
EDNRA--13857
LPAR1--4170
S1PR1--4301
AGTR1--16275
RXFP3--6996
EDN1--9540
LPAR3--11897
F2R--20036
TGM2--23204

Network

GO:0051482

Network
Enrichment
NameDescriptionExternal IDs
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
DRD2dopamine receptor D2 Entrez:1813  HPRD: 00539  Ensembl: ENSG00000149295  HGNC: 3023 
EDNRAendothelin receptor type A Entrez:1909  HGNC: 3179  Ensembl: ENSG00000151617  HPRD: 00571 
LPAR1lysophosphatidic acid receptor 1 Entrez:1902  HGNC: 3166  Ensembl: ENSG00000198121  HPRD: 03790 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DRD1dopamine receptor D1
CALCAcalcitonin-related polypeptide alpha
DRD2dopamine receptor D2
EDNRAendothelin receptor type A
LPAR1lysophosphatidic acid receptor 1
Query geneGeneGene descriptionEdge score
DRD1DRD1dopamine receptor D1
CALCACALCAcalcitonin-related polypeptide alpha
DRD2DRD2dopamine receptor D2
EDNRAEDNRAendothelin receptor type A
LPAR1LPAR1lysophosphatidic acid receptor 1

Troyanskaya Laboratory - Princeton University