ASD

GO:0010038 response to metal ion (219)

GeneInput weightStandardRank
SYT1--11
CAMK2B0.25155
GRIN2A0.25166
NEUROD2--98
PIK3R10.251150
KCNMA10.251191
SLC6A10.251313
EP300--1318
CALM3--352
ABCC8--1406
ASCL1--413
CACNA1G0.251443
ADCY10.251466
NEDD4L--495
NR3C1--496
JUND--509
JUN--511
KCNIP2--572
SNCA--1667
GRIN2B1.01763
KCNMB2--804
PCSK1--898
RYR2--1959
CALM1--1029
KCNK3--1065
CDKN1B--1162
MAPK8--1214
KCNIP1--1272
LEF1--1499
JUNB--1547
FOS--1680
KCNMB4--1767
BSG--1821
ATP5D--2148
ID2--2154
MAPK9--2237
SREBF2--2312
TSHB--2368
ATP7A--12483
BCL20.2512485
TRPC1--2648
PCNA--2671
SOD1--12702
SLC34A1--12748
NFATC3--2813
CALM2--2814
MEF2A--2837
TFAP2A--12923
ATP7B--12928
PTK2B--3063
ALDOB--3137
WNT5A--3319
PEF1--3473
SLC30A40.2513610
SLC18A1--3611
DRD20.2513749
LCT--3753
DUSP1--3785
CYP19A10.2513823
TSPO0.2514009
MTF10.2514011
GSK3A--4141
ABAT0.2514348
GPAM--4380
OTC--14449
IL1A--4651
ALB--4667
SCN5A--14668
TH0.2514933
TAT--15011
CYP1A10.2515067
PTGS20.2515085
ENTPD6--5240
PRNP--15418
AANAT0.2515448
TTN--15620
TPH20.2515693
FOSB0.2515694
MTTP--15845
INSR--15872
CRP--6053
PGAM2--6226
MAOB0.2516329
TFRC--6349
GIP--6352
SLC18A2--6423
NDRG1--16471
TNNT2--16745
IL4--6852
BNIP3--6953
HTR2B--6992
LIG4--17187
CASR--7200
SLC30A1--7241
NPPB--7334
ACTG1--17566
SLC6A30.517659
HMGCS1--7719
KCNMB3--7769
MTL5--7866
CCND1--17970
CYP11A10.2518063
APOB--8737
ARG2--8780
CTNNB10.519066
CEBPA--19079
AQP2--9426
FGA--19461
FGB--19587
PKLR--9956
HSD17B30.2519988
SLC25A120.2519996
TXNIP--10069
KCNMB1--10263
GIPR--10369
DBH0.25110495
KHK--10546
ZACN--11561
GPX10.25111644
HMGCS2--12061
CUTA--12077
TXNRD2--12148
KRT10--112191
GATM--112279
PDCD6--12294
RXRA0.25112299
APOBEC1--12314
MYOG--12349
ACTA1--12431
IL6--112695
SLC11A2--112770
CPS1--112820
ATP12A--12962
TFF1--13131
CYP2R1--13178
AQP9--13552
NEDD40.25114040
COX1--14254
QDPR0.25114344
BAG1--14923
IGFBP2--15026
ANXA11--15370
FGG--15642
PEBP1--15772
ACTB--15887
STIM1--17385
CASP12--18416
SHH--118571
HVCN1--19219
HAAO--19341
ARG1--119499
CACYBP--19557
D2HGDH--119566
NFKB1--20281
LCE1D--20510
CAPN3--120523
NOS3--20542
BGLAP--20875
LCAT--120976
S100A16--21190
MT1H--21308
TNFRSF11B--21340
CA2--121392
HSD17B20.25121493
MNAT1--21615
ITPR3--21697
VDR--21837
FABP4--21888
CLIC4--22003
CALR--22152
B2M--22154
SEC31A--22244
SERPINA1--122405
AQP1--22433
SDC1--22626
SOD2--22687
PLA2G4A--22727
S100A9--22828
MT1X--22860
ALOX5AP--123015
ALG2--23022
CASP6--23087
SOD3--23159
LTA4H--23171
BDH1--23265
S100A13--23446
GGH--23462
GSS--23506
CDH1--123589
SLC25A130.25123645
ICAM1--23720
IMPA1--23751
S100A8--23766
GSN--124007
ABCB6--24248
ATF1--24277
ASS1--124321
THBS1--24444
UROD--124523
AQP3--24575
ACADM--24580
CASP8--124587
PLCG2--24731
LCK--24753
KRT14--24854
CDK1--25053
PAM--25108
FSTL3--25154
CCNB1--25174
ADAM9--125221
CPOX--125236
CYBRD1--25244
XRCC4--25256
GPX3--25279
SPARC--25365
CAV1--125381
ACO1--25454
SLC30A5--25550
FXN--125604

Network

GO:0010038

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
NEUROD2neuronal differentiation 2
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
NEUROD2NEUROD2neuronal differentiation 2
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Troyanskaya Laboratory - Princeton University