ASD

GO:0016079 synaptic vesicle exocytosis (23)

GeneInput weightStandardRank
SYT1--11
SNAP250.25126
VAMP2--33
PCLO--154
SYNJ1--156
NLGN10.251276
STX1A0.251512
RIMS10.51777
RAB3A0.251848
DOC2A0.2511359
CPLX20.2511397
SNPH--1583
UNC13A--1859
SPTBN2--11935
SEPT5--2143
CPLX1--2778
OTOF--13498
CPLX3--4281
UNC13B--13412
STX4--13828
PSEN1--18523
BLOC1S6--21368
SNAPIN--23503

Network

GO:0016079

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PCLOpiccolo presynaptic cytomatrix protein Entrez:27445  HPRD: 16078  HGNC: 13406  Ensembl: ENSG00000186472 
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
SNAP25synaptosomal-associated protein, 25kDa
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOpiccolo presynaptic cytomatrix protein
SYNJ1synaptojanin 1
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
SNAP25SNAP25synaptosomal-associated protein, 25kDa
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOPCLOpiccolo presynaptic cytomatrix protein
SYNJ1SYNJ1synaptojanin 1

Troyanskaya Laboratory - Princeton University