ASD

GO:0002862 negative regulation of inflammatory response to antigenic stimulus (5)

GeneInput weightStandardRank
PSMB4--1091
IL12B--3596
SPN--12057
NOD2--121514
IL20RB--22045

Network

GO:0002862

Network
Enrichment
NameDescriptionExternal IDs
PSMB4proteasome (prosome, macropain) subunit, beta type, 4 Entrez:5692  Ensembl: ENSG00000159377  HGNC: 9541  HPRD: 03710 
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Entrez:3593  HGNC: 5970  Ensembl: ENSG00000113302  HPRD: 01194 
SPNsialophorin Entrez:6693  Ensembl: ENSG00000197471  HGNC: 11249  HPRD: 06770 
NOD2nucleotide-binding oligomerization domain containing 2 Entrez:64127  HGNC: 5331  HPRD: 05810  Ensembl: ENSG00000167207 
IL20RBinterleukin 20 receptor beta Entrez:53833  HGNC: 6004  Ensembl: ENSG00000174564  HPRD: 14594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMB4proteasome (prosome, macropain) subunit, beta type, 4
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
SPNsialophorin
NOD2nucleotide-binding oligomerization domain containing 2
IL20RBinterleukin 20 receptor beta
Query geneGeneGene descriptionEdge score
PSMB4PSMB4proteasome (prosome, macropain) subunit, beta type, 4
IL12BIL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
SPNSPNsialophorin
NOD2NOD2nucleotide-binding oligomerization domain containing 2
IL20RBIL20RBinterleukin 20 receptor beta

Troyanskaya Laboratory - Princeton University