ASD

GO:0070201 regulation of establishment of protein localization (222)

GeneInput weightStandardRank
YWHAB0.251107
PIK3R10.251150
GNAQ--189
UBR5--193
SOX4--250
EP300--1318
NF10.251372
CADM10.251391
GSK3B--427
SNAP91--546
PRKCI--568
G3BP2--610
CLIP3--730
SMAD4--821
SMAD3--823
TGFB2--834
FBXW11--859
PCSK1--898
EDA--1925
ZIC1--939
AKT10.2511020
GAPVD1--1061
XPO1--1095
APC2--1115
PKIA--1118
BMP7--1137
BMPR1A--1140
CX3CL1--1199
SIRT1--1233
FZD7--1357
TXN--1408
MIF0.2511552
PDPK1--1740
AKAP5--1759
MXI1--11763
AR0.2511902
SPECC1L--1912
ACHE--2025
RAB11A--2051
RHOA--2292
EPB41L5--2335
GATA3--2376
PSMD10--2412
EGFR--12546
SCAMP50.2512682
LATS1--2781
WNK30.2512810
CDK50.2513194
ARF6--3317
WNT5A--3319
RBP4--3448
DAB2IP--3482
TCF7L20.513548
IL12B--3596
UHMK1--3601
DRD20.2513749
PPP2R5A--3979
AKAP1--4078
IRF3--4175
AXIN2--14260
FLNA--14285
DRD30.2514349
GPAM--4380
MAPK7--4384
AXIN1--14419
CYLD--14624
IL1A--4651
WNT3A--4747
FNDC1--4763
NLRP30.2514959
SFRP2--5252
BARD1--15343
NFKBIA--5569
ADIPOQ0.2516032
PLA2G1B--6059
KEAP1--6103
NR1H2--6183
CIDEA--6211
GLI3--16261
RHOG--6279
SORBS1--6411
BMP4--16499
CNST--6559
BCL2L1--6563
NDFIP1--6744
GOPC--6764
TNFSF15--6782
HTR2B--6992
SERGEF--6993
DRD40.2517021
TNFSF4--7262
TGFBR1--17268
CD40LG--7577
IFNA2--7694
CDKN1A--7714
LACRT--7733
IL2--7838
P2RX7--7888
BCL3--7998
RPH3AL--8235
ADORA2A0.2518408
BAMBI--8550
EXOC4--8678
CHIA--9216
PIK3C3--9358
IL10--19513
PRKACA--9630
IL5--9669
PKDCC--9871
APPL1--10112
NDFIP2--10157
EDAR--110537
IL1B--110818
FFAR4--10968
PYDC1--11053
IL23A--11134
SFRP5--11273
IL26--11645
MBTPS1--11794
LEP0.25111864
WWP2--11885
CLEC6A--12440
FOXP3--112457
IL6--112695
TLR4--112795
KRT20--12797
IFNG--112827
VEGFC--12850
EGF0.25112881
IL13--12888
UACA--12955
TGFB3--113097
CRTAM--13317
TLR9--13360
TLR7--13389
MDFI--13519
IL33--13620
RHOQ--14092
CCL19--14578
APOA2--14659
CLEC9A--14752
RBPMS--14967
TNF0.25115243
PRKCQ--15381
GLMN--16462
SHH--118571
APOA1--118958
TLR2--119246
EPHA2--119467
GCC2--19484
POU5F1--19704
NFKBIE--19710
NLRP12--19807
F2RL1--19969
EMD--120034
F2R--20036
TGFB10.25120135
JUP--120291
NFKBIL1--20431
NLRP1--20532
CDKN2A--120587
IL4R--20610
TONSL--20639
TNFRSF4--20689
FZD1--20775
ARFIP1--20938
PANX1--21011
TRIP6--21037
MTOR--21095
ARHGEF16--21200
SRGN--21336
NOD2--121514
TACC3--21671
MDFIC--21692
NLRP2--21787
ADAM8--21797
BTN2A2--21999
C5--122004
INS--122047
PKIG--22117
PYCARD--22145
TNFSF14--22260
LRP1--22276
CCR7--22367
SAA1--22464
TLR3--22478
DDX58--22544
RBCK1--22556
CARD8--22573
ANXA10.5122810
CD27--22836
TRIM16--22841
TNFRSF1A--22842
NFKBIB--22875
HNF4A--122965
DISP1--22983
CD14--22990
RHBDF1--23088
RHBDF2--23158
FAF1--23304
MAVS--23348
LCP1--23490
CDH1--123589
CD36--23662
TRAF2--23686
SNAI2--123962
SPHK1--24069
SAA2--24171
WWTR1--24317
DNAJC1--24415
TMEM173--24599
OGG1--124604
WIPF1--24668
ANG--124879
KCNN4--24952
NR1H3--25006
CDK1--25053
DPH3--25120
ADAM9--125221
CD40--25231
LDLRAP1--25289
NOLC1--25515

Network

GO:0070201

Network
Enrichment
NameDescriptionExternal IDs
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
GNAQguanine nucleotide binding protein (G protein), q polypeptide
UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX4SRY (sex determining region Y)-box 4
Query geneGeneGene descriptionEdge score
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX4SOX4SRY (sex determining region Y)-box 4

Troyanskaya Laboratory - Princeton University