ASD

GO:0010812 negative regulation of cell-substrate adhesion (21)

GeneInput weightStandardRank
FZD7--1357
PTEN1.011389
RASA1--1983
FZD4--12229
BCL6--2550
NOTCH1--12865
HOXA7--3411
WNT1--4383
ARHGAP6--5374
TBCD--5702
NF2--15991
LGALS1--6065
PLG--9166
ANGPT2--10581
ACVRL1--111656
MMP14--12920
CDKN2A--120587
ACER2--20862
COL1A1--124140
THBS1--24444
SERPINE10.25125055

Network

GO:0010812

Network
Enrichment
NameDescriptionExternal IDs
FZD7frizzled family receptor 7 Entrez:8324  HGNC: 4045  HPRD: 04560  Ensembl: ENSG00000155760 
PTENphosphatase and tensin homolog Entrez:5728  HGNC: 9588  HPRD: 03431 
RASA1RAS p21 protein activator (GTPase activating protein) 1 Entrez:5921  HPRD: 00745  Ensembl: ENSG00000145715  HGNC: 9871 
FZD4frizzled family receptor 4 Entrez:8322  HPRD: 05203  Ensembl: ENSG00000174804  HGNC: 4042 
BCL6B-cell CLL/lymphoma 6 Entrez:604  HGNC: 1001  Ensembl: ENSG00000113916  HPRD: 00180 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FZD7frizzled family receptor 7
PTENphosphatase and tensin homolog
RASA1RAS p21 protein activator (GTPase activating protein) 1
FZD4frizzled family receptor 4
BCL6B-cell CLL/lymphoma 6
Query geneGeneGene descriptionEdge score
FZD7FZD7frizzled family receptor 7
PTENPTENphosphatase and tensin homolog
RASA1RASA1RAS p21 protein activator (GTPase activating protein) 1
FZD4FZD4frizzled family receptor 4
BCL6BCL6B-cell CLL/lymphoma 6

Troyanskaya Laboratory - Princeton University