ASD

GO:0051789 response to protein stimulus (160)

GeneInput weightStandardRank
GRIN2A0.25166
TTC3--68
PAFAH1B10.25174
PIK3R10.251150
DNAJB6--222
FGFR2--1237
EP300--1318
MAP1B--403
DNAJA1--445
NR3C1--496
DEK--609
SETD20.251672
HSP90AA1--727
GRIN2B1.01763
HSPE1--778
ACTR3--803
PCSK1--898
NR4A20.251992
MEIS2--1041
CUL31.011093
DGKI--1124
CBLB--1161
ADCYAP1R1--1273
CCNA1--1668
FOS--1680
UBXN4--1761
PPP1R15A--2011
ID2--2154
MSX2--12260
DNAJB5--2373
EIF4A2--2547
YOD1--2571
NRP20.2512603
HSPH1--2678
EGR1--3062
MSX1--13127
ALDOB--3137
VASH10.2513148
TGIF1--13264
KLF10--3457
DDR1--3647
CYP19A10.2513823
ITGB1--3903
HSP90AB1--3924
CYP17A10.2513984
APCS--4060
VEGFA0.2514087
STUB1--4250
FGF10--14532
FAF2--4753
HSPD1--14908
TH0.2514933
PLXNA4--5391
HSPA8--5713
INSR--15872
CST3--15894
DDC0.2515929
DNAJB2--6026
DNAJB1--6034
VAPB--16133
BCL2L1--6563
CREB3L2--6585
HSPB3--16594
DNAJC3--6725
BOC--6901
RNF5--7182
HERPUD2--7341
VCP--7434
HSPA4--7593
HMGCS1--7719
NFE2L2--7853
MET1.018002
CYP11A10.2518063
CHAC1--8177
ID1--9040
CD4--9401
EDN1--9540
HNF1B--19881
ERN1--9939
LYN--10336
GIPR--10369
DBH0.25110495
ANGPT2--10581
OXT0.25111176
SERP1--11460
TOR1A--11468
HMGCS2--12061
HERPUD1--12415
HSPA1A--12423
IL6--112695
ZFP57--12704
WFS10.25112793
IFNG--112827
HSPA4L--13175
CREB3L3--13337
UBE2J2--13641
ATF6B--14301
HSPA1L--14537
ALOX12--14851
DDIT3--14883
SNORA4--15763
HDAC6--16779
SNORA63--17637
SNORA81--17724
SNORD2--17743
MIR1248--17812
CASP12--18416
HSPA7--18480
HSPA1B--18501
HSD17B10--18803
HSPA5--19143
DDB1--19185
ARG1--119499
HSPA2--20026
DERL3--20109
TGFB10.25120135
ATF6--20267
EIF2AK3--20456
CD44--20701
CREB3L4--20714
ERP44--20743
DERL2--20749
AMFR--20817
BGLAP--20875
F12--121126
PGGT1B--21149
BAK1--21229
EIF2AK4--21300
XBP1--21326
EIF2AK2--21530
HSPA6--21842
DERL1--22108
CD48--22204
EDEM1--22357
EDEM2--22497
CYR61--22574
HSPB7--22630
ID3--22679
AARS--22782
HSD17B7--22793
EDEM3--22871
CREB3L1--22904
DNAJB4--23008
CCL5--23042
HSPB1--123318
HSPB2--23389
JKAMP--23394
FBXO6--23542
MANF--23687
ERO1L--23981
CUL4A--24230
CTSV--24505
TOR1B--24890
CDK1--25053
CCNB1--25174
LCN2--25233
CLU--25437
SERPINH1--25570
CTSB--25627
DNAJC4--25711

Network

GO:0051789

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
TTC3tetratricopeptide repeat domain 3 Entrez:7267  HPRD: 03773  HGNC: 12393  Ensembl: ENSG00000182670 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6 Entrez:10049  HGNC: 14888  Ensembl: ENSG00000105993  HPRD: 07107 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
TTC3tetratricopeptide repeat domain 3
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
TTC3TTC3tetratricopeptide repeat domain 3
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
DNAJB6DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6

Troyanskaya Laboratory - Princeton University