ASD

GO:0031333 negative regulation of protein complex assembly (55)

GeneInput weightStandardRank
BCL11A1.0132
MAPRE1--331
STMN2--343
GSK3B--427
PFN2--551
THRA--614
SLIT2--659
SNCA--1667
CLIP3--730
PRKCZ--991
CDC42--1138
KANK1--1150
SPTAN1--11287
DMTN--1465
SPTBN4--1647
SPTBN2--11935
TMSB10--2139
CAPZB--2179
SMAD6--2305
ADD2--2388
ADD1--12876
TMSB15A--2947
TMSB15B--3139
HEY2--3174
RAF10.2513236
SPTB--3478
SPTBN1--3627
INPP5J--3690
CRBN--4203
CAPZA2--4483
RDX--14697
CAPZA1--4983
SPTBN5--5319
CTNNBIP1--5675
TBCD--5702
TMSB4X--6302
SOST--6885
SPTA1--16958
AVIL--7943
CAPZA3--8396
STMN1--9278
SCIN--9620
TWF1--11060
DKK1--11567
TMSB4Y--13524
TMSB4XP8--14081
TMSB4XP4--17717
CAPG--20663
VIL10.5122243
VILL--22283
EIF4EBP1--22803
TWF2--23010
GSN--124007
TRIOBP--124113
CLU--25437

Network

GO:0031333

Network
Enrichment
NameDescriptionExternal IDs
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) Entrez:53335  Ensembl: ENSG00000119866  HGNC: 13221  HPRD: 05949 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2stathmin-like 2
GSK3Bglycogen synthase kinase 3 beta
PFN2profilin 2
Query geneGeneGene descriptionEdge score
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2STMN2stathmin-like 2
GSK3BGSK3Bglycogen synthase kinase 3 beta
PFN2PFN2profilin 2

Troyanskaya Laboratory - Princeton University