ASD

GO:0055067 monovalent inorganic cation homeostasis (44)

GeneInput weightStandardRank
SLC12A5--141
KCNMA10.251191
NEDD4L--495
KCNJ10--1733
KCNA5--1743
SLC9A6--1259
NR3C20.511624
NOX1--1924
EDNRB--12042
SLC26A4--12230
SLC9A5--4012
MAFG--4115
SLC9A2--4138
CLCN3--4307
SLC26A9--4885
ATP6V1H--5369
FASLG--15523
SLC9A7--5618
ATP6V0A4--7653
SLC9A1--7776
ATP4A--8774
TMPRSS3--18916
SLC9A91.019004
SLC9A3--9044
EDN1--9540
ATP6V0E2--10017
ATP1A4--10368
CLN3--110442
ATP6V1B1--10564
SLC9A4--11933
AQP11--12001
ATP12A--12962
AGT--113305
CYP11B2--13660
PPT1--113834
UPK3A--118248
SLC9A8--19558
ATP5B--21365
GPR89A--22689
RHCG--22911
SLC11A1--23561
CLN6--124022
ATP6V0E1--25547
CLN5--125742

Network

GO:0055067

Network
Enrichment
NameDescriptionExternal IDs
SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5 Entrez:57468  Ensembl: ENSG00000124140  HGNC: 13818  HPRD: 09469 
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Entrez:23327  HGNC: 7728  HPRD: 05903  Ensembl: ENSG00000049759 
KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10 Entrez:3766  Ensembl: ENSG00000177807  HGNC: 6256  HPRD: 03732 
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5 Entrez:3741  Ensembl: ENSG00000130037  HPRD: 08888  HGNC: 6224 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5
Query geneGeneGene descriptionEdge score
SLC12A5SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
NEDD4LNEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
KCNJ10KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10
KCNA5KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5

Troyanskaya Laboratory - Princeton University