ASD

GO:0031345 negative regulation of cell projection organization (52)

GeneInput weightStandardRank
BCL11A1.0132
SLIT1--61
PAFAH1B10.25174
ARHGDIA--109
SEMA4F--303
STMN2--343
SLIT2--659
OMG0.251808
RUFY3--906
ULK1--1008
HDAC2--1440
THY1--1580
DCC--1687
YWHAH--2009
XYLT1--12057
MBP--2120
RNF6--12235
KIAA0319--2279
RHOA--2292
CIT--2320
GFAP--12475
PTK20.2512488
RTN4--2735
NRP1--2807
WNT5A--3319
SEMA3A--3494
INPP5J--3690
TNR--3868
ITGB1--3903
ITM2C--4102
LPAR1--4170
WNT3--4613
INPPL1--4681
WNT3A--4747
PTPRF--5040
RYK--5383
MAG--5765
NTN1--6023
TLX2--6047
LGALS1--6065
NGFR0.2516212
RTN4R--6304
LINGO1--6321
SPP1--12442
PMP22--113921
KATNA1--14335
TRPV4--115988
PSEN1--18523
DGUOK--18662
ARHGEF1--21297
KLK8--22593
FKBP4--23829

Network

GO:0031345

Network
Enrichment
NameDescriptionExternal IDs
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) Entrez:53335  Ensembl: ENSG00000119866  HGNC: 13221  HPRD: 05949 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
ARHGDIARho GDP dissociation inhibitor (GDI) alpha Entrez:396  HGNC: 678  Ensembl: ENSG00000141522  HPRD: 03565 
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F Entrez:10505  HGNC: 10734  HPRD: 04748 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SLIT1slit homolog 1 (Drosophila)
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
ARHGDIARho GDP dissociation inhibitor (GDI) alpha
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
Query geneGeneGene descriptionEdge score
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SLIT1SLIT1slit homolog 1 (Drosophila)
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
ARHGDIAARHGDIARho GDP dissociation inhibitor (GDI) alpha
SEMA4FSEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F

Troyanskaya Laboratory - Princeton University