ASD

GO:0051865 protein autoubiquitination (26)

GeneInput weightStandardRank
CNOT4--197
PARK20.251952
RNF4--973
RCHY1--1615
UBE2A0.2513019
TRIM13--3602
UBE2B--4057
STUB1--4250
UHRF2--4314
RNF13--5400
RNF220--6259
MARCH5--6331
RNF115--6467
RNF146--7910
RNF133--8789
RAG1--10790
TRAF6--11055
LRSAM1--13116
TRIM17--15015
RNF187--20424
ERCC8--120608
TRIM68--23520
TRAF2--23686
BRCA1--124573
TRIM21--24895
DDB2--125337

Network

GO:0051865

Network
Enrichment
NameDescriptionExternal IDs
CNOT4CCR4-NOT transcription complex, subunit 4 Entrez:4850  HGNC: 7880  HPRD: 05369  Ensembl: ENSG00000080802 
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
RNF4ring finger protein 4 Entrez:6047  HPRD: 04167  Ensembl: ENSG00000063978  HGNC: 10067 
RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase Entrez:25898  Ensembl: ENSG00000163743  HGNC: 17479  HPRD: 07607 
UBE2Aubiquitin-conjugating enzyme E2A Entrez:7319  HPRD: 02422  HGNC: 12472  Ensembl: ENSG00000077721 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNOT4CCR4-NOT transcription complex, subunit 4
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
RNF4ring finger protein 4
RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
UBE2Aubiquitin-conjugating enzyme E2A
Query geneGeneGene descriptionEdge score
CNOT4CNOT4CCR4-NOT transcription complex, subunit 4
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
RNF4RNF4ring finger protein 4
RCHY1RCHY1ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
UBE2AUBE2Aubiquitin-conjugating enzyme E2A

Troyanskaya Laboratory - Princeton University