ASD

GO:0002683 negative regulation of immune system process (125)

GeneInput weightStandardRank
CNR10.25129
PLCB1--148
SOX11--96
ABR--160
SFRP1--387
SOCS5--463
SLIT2--659
TGFB2--834
ADORA1--960
SOX9--1970
PSMB4--1091
CBLB--1161
THY1--1580
PPP3CB--1731
BCR--11839
SPECC1L--1912
NR1D1--1920
MASP1--2021
ELF1--2054
ID2--2154
RC3H1--2217
BCL6--2550
ITCH--2932
HOXA7--3411
FOXF1--13518
IL12B--3596
ATM--13622
DLG1--3822
GREM1--3867
FLT3--14055
IRF3--4175
PRDM1--4368
TNFAIP3--4469
IL2RA--4611
INHA--4765
DUSP10--5172
IFNB1--5250
DTX1--5290
PRNP--15418
PAG1--5486
PRDX2--5497
PDE5A--5684
PCBP2--6256
GLI3--16261
BMP4--16499
NDFIP1--6744
IL4--6852
CTLA4--6866
IHH--17160
TNFSF4--7262
FOXJ1--7628
IFNA2--7694
XCL1--7819
IL2--7838
ADORA2A0.2518408
DUSP3--8506
SFTPD--8649
SPINK5--18777
PTPRJ--19136
IL10--19513
IFNL1--10151
CD274--10317
TAP1--110380
LAX1--10483
ARRB2--10647
GIMAP5--10690
VTCN1--11344
CNR20.25111649
SLA2--11651
IL31RA--11821
SPN--12057
SCGB1A1--12372
FOXP3--112457
UBASH3A--12815
TGFB3--113097
NFKBID--13229
TLR9--13360
TIGIT--13464
PAWR--13478
IL33--13620
PDCD1LG2--13634
CD276--13688
GAL--13897
NRARP--14597
IRAK3--14633
LAG3--15302
GLMN--16462
INHBA--16974
SHH--118571
SAMSN1--19930
F2RL1--19969
AMBP--20003
TRAFD1--20096
TGFB10.25120135
JAK3--20340
CDKN2A--120587
BPI--20592
IL4R--20610
TNFRSF13B--121223
VSIG4--21323
MNDA--21393
NOD2--121514
PTPRC--21546
PTPN22--121899
LST1--21924
BTN2A2--21999
C5--122004
IL20RB--22045
INS--122047
COL3A1--122855
IDO1--23074
ERBB2--123130
CCR2--23296
INPP5D--23776
HMOX1--23938
CD74--24030
A2M--24058
ZC3H8--24341
IFIT1--24398
THBS1--24444
TARBP2--24667
ADA0.5124751
NR1H3--25006
MICB--25021
SERPING1--125126

Network

GO:0002683

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SOX11SRY (sex determining region Y)-box 11
ABRactive BCR-related
SFRP1secreted frizzled-related protein 1
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SOX11SOX11SRY (sex determining region Y)-box 11
ABRABRactive BCR-related
SFRP1SFRP1secreted frizzled-related protein 1

Troyanskaya Laboratory - Princeton University