GO:0070102 interleukin-6-mediated signaling pathway (5)

GeneInput weightStandardRank
GAB1--1198
IL6ST--3678
STAT3--18538
IL6--112695
IL6R--19897

Network

GO:0070102

Network
Enrichment
NameDescriptionExternal IDs
GAB1GRB2-associated binding protein 1 Entrez:2549  HPRD: 05116  Ensembl: ENSG00000109458  HGNC: 4066 
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) Entrez:3572  HGNC: 6021  Ensembl: ENSG00000134352  HPRD: 02824 
STAT3signal transducer and activator of transcription 3 (acute-phase response factor) Entrez:6774  Ensembl: ENSG00000168610  HGNC: 11364  HPRD: 00026 
IL6interleukin 6 (interferon, beta 2) Entrez:3569  HGNC: 6018  HPRD: 00970  Ensembl: ENSG00000136244 
IL6Rinterleukin 6 receptor Entrez:3570  HGNC: 6019  HPRD: 01000  Ensembl: ENSG00000160712 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GAB1GRB2-associated binding protein 1
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)
IL6interleukin 6 (interferon, beta 2)
IL6Rinterleukin 6 receptor
Query geneGeneGene descriptionEdge score
GAB1GAB1GRB2-associated binding protein 1
IL6STIL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)
STAT3STAT3signal transducer and activator of transcription 3 (acute-phase response factor)
IL6IL6interleukin 6 (interferon, beta 2)
IL6RIL6Rinterleukin 6 receptor