ASD

GO:0003085 negative regulation of systemic arterial blood pressure (9)

GeneInput weightStandardRank
BMPR2--1281
CALCA--1013
ADRB1--1057
ADRA1A--1858
AGTR20.2511955
ADRB3--12953
ADRA1D--7837
SOD2--22687
ADRB20.25123251

Network

GO:0003085

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
AGTR2angiotensin II receptor, type 2 Entrez:186  HPRD: 02071  HGNC: 338  Ensembl: ENSG00000180772 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
CALCAcalcitonin-related polypeptide alpha
ADRB1adrenoceptor beta 1
ADRA1Aadrenoceptor alpha 1A
AGTR2angiotensin II receptor, type 2
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
CALCACALCAcalcitonin-related polypeptide alpha
ADRB1ADRB1adrenoceptor beta 1
ADRA1AADRA1Aadrenoceptor alpha 1A
AGTR2AGTR2angiotensin II receptor, type 2

Troyanskaya Laboratory - Princeton University