ASD

GO:0050804 regulation of synaptic transmission (162)

GeneInput weightStandardRank
ATP2B20.513
CNR10.25129
CTNND21.0134
NTRK20.25151
CAMK2B0.25155
KRAS--157
GRIN2A0.25166
ADNP1.0171
ERBB40.25186
NEUROD2--98
HTR2A0.251121
PRKCE--204
GRIK20.51232
GRM50.251240
PPP3CA--244
CAMK2A--249
GABBR10.251264
CACNA1A--1270
NLGN10.251276
GRIN1--294
SLC6A10.251313
RASGRF1--335
NF10.251372
DBN1--385
MAP1B--403
MAPK8IP2--418
MEF2C0.251428
GRIK1--481
CALB10.251484
STX1A0.251512
PFN2--551
CRHR1--589
GRM3--652
SNCA--1667
CNTN2--674
USP46--708
NPY5R0.251725
TAC10.251726
KCNJ10--1733
GRIN2B1.01763
STXBP1--769
RIMS10.51777
BDNF0.251791
CCKBR--794
RAB3A0.251848
NOS10.251853
DLG4--857
DRD10.251899
RAPGEF40.251904
LGI1--923
NCDN--950
PARK20.251952
ADORA1--960
GRM10.251975
NR2E10.251977
SNCAIP--1042
BHLHE40--1054
DRD50.2511103
GRIK30.2511247
GNAI3--1262
CHRNA3--1266
CPLX20.2511397
GRM80.2511404
GNAI1--1468
GRIA4--1474
EDN3--11577
KCNMB4--1767
VGF0.2511782
CHRNA70.511837
YWHAG--1857
ADRA1A--1858
UNC13A--1859
BCAN--1869
SPECC1L--1912
NISCH--1913
YWHAH--2009
ACHE--2025
RAB11A--2051
PPFIA3--2061
KCNC3--12203
SLC24A2--2302
GFAP--12475
CNTN41.012492
KCNC4--2573
NETO1--2632
BCHE--2809
MEF2A--2837
EGR1--3062
SYP--3133
CDK50.2513194
NPTN--3227
NTF30.2513232
SNCG--3502
SLC18A1--3611
SERPINE2--3708
DRD20.2513749
TNR--3868
SLC6A40.2514137
SYNGR1--4153
S100B--4199
PXK--4240
CPLX3--4281
DRD30.2514349
GDNF--14658
CHRNB4--4903
ANAPC2--5008
PTGS20.2515085
HRAS0.2515086
NLGN2--5147
GNAI2--5860
ADIPOQ0.2516032
NGF0.2516229
EGR20.2516247
NAPB--6293
GIP--6352
OXTR0.516388
OPHN10.516584
DRD40.2517021
SLC30A1--7241
SLC1A30.2517455
HTR1B0.2518092
ADORA2A0.2518408
ARC0.2518587
KISS1R--9434
EDN1--9540
PRKACA--9630
GIPC1--9877
ABHD6--10063
UCN--10358
CPLX4--10481
CHAT--10603
ARRB2--10647
OXT0.25111176
TACR1--11618
HCRT0.25111633
CNR20.25111649
SHISA9--12388
PMCH--12542
IFNG--112827
KCNQ4--112849
RGS14--12999
AGT--113305
UNC13B--13412
MYLK2--113626
NRAS--114119
MGLL--14193
TNF0.25115243
PEBP1--15772
PATE4--16019
PSEN1--18523
PINK1--118609
P2RX3--18725
CHRNB20.25120216
CHRFAM7A--20694
GRID2IP--21156
CD380.25121442
NMU--22143
PLAT--22444
PSEN2--23095
APOE0.25123516
MMP9--24369
CDC20--25608

Network

GO:0050804

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
CTNND2catenin (cadherin-associated protein), delta 2 Entrez:1501  HGNC: 2516  HPRD: 09181  Ensembl: ENSG00000169862 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
CNR1cannabinoid receptor 1 (brain)
CTNND2catenin (cadherin-associated protein), delta 2
NTRK2neurotrophic tyrosine kinase, receptor, type 2
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
CNR1CNR1cannabinoid receptor 1 (brain)
CTNND2CTNND2catenin (cadherin-associated protein), delta 2
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta

Troyanskaya Laboratory - Princeton University