ASD

GO:0030166 proteoglycan biosynthetic process (26)

GeneInput weightStandardRank
XYLT1--12057
IGF10.2512793
GLCE--2804
CHSY1--3526
HS3ST50.2513697
GAL3ST3--4180
HS6ST1--4217
EXT10.2514780
HS3ST3B1--5069
NDST1--5114
CHST8--5529
CHST9--5902
FOXL1--6313
CSGALNACT1--8453
CHST11--9003
SLC35D1--11263
HS2ST1--11391
CHST13--14858
NDST2--15016
GAL3ST4--18325
CHST7--19095
CHST3--22182
CHST12--22490
DSE--23812
CSGALNACT2--24745
EXT2--125243

Network

GO:0030166

Network
Enrichment
NameDescriptionExternal IDs
XYLT1xylosyltransferase I Entrez:64131  HGNC: 15516  HPRD: 12168  Ensembl: ENSG00000103489 
IGF1insulin-like growth factor 1 (somatomedin C) Entrez:3479  HPRD: 00936  Ensembl: ENSG00000017427  HGNC: 5464 
GLCEglucuronic acid epimerase Entrez:26035  HGNC: 17855  HPRD: 07020  Ensembl: ENSG00000138604 
CHSY1chondroitin sulfate synthase 1 Entrez:22856  HGNC: 17198  Ensembl: ENSG00000131873  HPRD: 10493 
HS3ST5heparan sulfate (glucosamine) 3-O-sulfotransferase 5 Entrez:222537  Ensembl: ENSG00000249853  HGNC: 19419  HPRD: 13674 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
XYLT1xylosyltransferase I
IGF1insulin-like growth factor 1 (somatomedin C)
GLCEglucuronic acid epimerase
CHSY1chondroitin sulfate synthase 1
HS3ST5heparan sulfate (glucosamine) 3-O-sulfotransferase 5
Query geneGeneGene descriptionEdge score
XYLT1XYLT1xylosyltransferase I
IGF1IGF1insulin-like growth factor 1 (somatomedin C)
GLCEGLCEglucuronic acid epimerase
CHSY1CHSY1chondroitin sulfate synthase 1
HS3ST5HS3ST5heparan sulfate (glucosamine) 3-O-sulfotransferase 5

Troyanskaya Laboratory - Princeton University