ASD

GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (6)

GeneInput weightStandardRank
CALM3--352
RYR2--1959
CALM1--1029
FKBP1B--2346
CALM2--2814
CASQ1--2959

Network

GO:0010880

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
FKBP1BFK506 binding protein 1B, 12.6 kDa Entrez:2281  Ensembl: ENSG00000119782  HPRD: 02795  HGNC: 3712 
CALM2calmodulin 2 (phosphorylase kinase, delta) Entrez:805  HPRD: 00242  HGNC: 1445  Ensembl: ENSG00000143933 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
RYR2ryanodine receptor 2 (cardiac)
CALM1calmodulin 1 (phosphorylase kinase, delta)
FKBP1BFK506 binding protein 1B, 12.6 kDa
CALM2calmodulin 2 (phosphorylase kinase, delta)
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
RYR2RYR2ryanodine receptor 2 (cardiac)
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)
FKBP1BFKBP1BFK506 binding protein 1B, 12.6 kDa
CALM2CALM2calmodulin 2 (phosphorylase kinase, delta)

Troyanskaya Laboratory - Princeton University